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Large-scale analysis of the GRAS gene family in Arabidopsis thaliana
GRAS proteins belong to a plant-specific transcription factor family. Currently, 33 GRAS members including a putative expressed pseudogene have been identified in the Arabidopsis genome. With aExpand
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Functional consequences of frizzled-7 receptor overexpression in human hepatocellular carcinoma.
BACKGROUND & AIMS The molecular pathogenesis of human hepatocellular carcinoma (HCC) is understood poorly. In some tumors, activation of the Wnt/beta-catenin pathway as a result of beta-catenin geneExpand
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Wnt/Frizzled signaling in hepatocellular carcinoma.
  • H. Lee, M. Kim, J. Wands
  • Biology, Medicine
  • Frontiers in bioscience : a journal and virtual…
  • 1 May 2006
The Wnt/Frizzled (FZD) signaling cascade is important for cell fate determination during embryonic development as well as maintaining tissue homeostasis in the adult. In addition to these physiologicExpand
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Conservation and Diversification of SCARECROW in Maize
The SCARECROW (SCR) gene in Arabidopsis is required for asymmetric cell divisions responsible for ground tissue formation in the root and shoot. Previously, we reported that Zea mays SCARECROWExpand
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Loss of Raf kinase inhibitor protein promotes cell proliferation and migration of human hepatoma cells.
BACKGROUND & AIMS The Raf kinase inhibitor protein (RKIP) has been identified as a suppressor of the mitogen-activated protein kinase (MAPK) pathway. Loss of RKIP function promotes tumor metastasisExpand
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PLASTID DYNAMICS DURING SURVIVAL OF DINOPHYSIS CAUDATA WITHOUT ITS CILIATE PREY 1
To survive, the marine dinoflagellate Dinophysis caudata Saville‐Kent must feed on the plastidic ciliate Myrionecta rubra (=Mesodinium rubrum), itself a consumer of cryptophytes. Whether D. caudataExpand
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DINOPHYSIS CAUDATA (DINOPHYCEAE) SEQUESTERS AND RETAINS PLASTIDS FROM THE MIXOTROPHIC CILIATE PREY MESODINIUM RUBRUM 1
“Phototrophic”Dinophysis Ehrenberg species are well known to have chloroplasts of a cryptophyte origin, more specifically of the cryptophyte genus complex Teleaulax/Geminigera. Nonetheless, whetherExpand
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Tissue distribution of P2X4 receptors studied with an ectodomain antibody
Abstract.A monoclonal antibody was developed to the extracellular domain of the rat P2X4 receptor. The antibody was highly selective among all rat P2X receptor subunits, and recognised only theExpand
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Expression of transforming growth factor β1 promotes cholangiocarcinoma development and progression.
BACKGROUND AND AIMS The role of transforming growth factor beta 1 (TGFβ1) in cholangiocarcinoma (CCA) initiation and growth requires further definition. METHODS We employed pharmacological andExpand
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Pharmacological inhibition of Frizzled-7 displays anti-tumor properties in hepatocellular carcinoma.
BACKGROUND & AIMS We previously reported the frequent overexpression of the FZD7 membrane receptor in hepatocellular carcinoma (HCC) and its role for controlling cancer phenotype. Herein, this studyExpand
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