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Role of p38 Mitogen-Activated Protein Kinase in Axotomy-Induced Apoptosis of Rat Retinal Ganglion Cells
p38 is a member of the mitogen-activated protein (MAP) kinase superfamily and mediates intracellular signal transduction. Recent studies suggest that p38 is involved in apoptotic signaling in several… Expand
Identification and disruption analysis of the recN gene in the extremely radioresistant bacterium Deinococcus radiodurans.
- T. Funayama, I. Narumi, M. Kikuchi, S. Kitayama, H. Watanabe, K. Yamamoto
- Biology, Medicine
- Mutation research
- 22 October 1999
We isolated a radiosensitive mutant strain, KR4128, from a wild-type strain of Deinococcus radiodurans, which is known as a extremely radioresistant bacterium. The gene that restore the defect of the… Expand
The LexA protein from Deinococcus radiodurans is not involved in RecA induction following gamma irradiation.
The involvement of LexA in induction of RecA was investigated in Deinococcus radiodurans. As in the wild-type strain, an increase in RecA protein synthesis following gamma irradiation was detected in… Expand
Characterization of pathways dependent on the uvsE, uvrA1, or uvrA2 gene product for UV resistance in Deinococcus radiodurans.
The genome of a radiation-resistant bacterium, Deinococcus radiodurans, contains one uvsE gene and two uvrA genes, uvrA1 and uvrA2. Using a series of mutants lacking these genes, we determined the… Expand
Suppression of stress immobilization-induced phosphorylation of ERK 1/2 by biting in the rat hypothalamic paraventricular nucleus
- K. Sasaguri, M. Kikuchi, N. Hori, N. Yuyama, S. Sato
- Biology, Medicine
- Neuroscience Letters
- 22 July 2005
We have previously reported that acute immobilization stress induces Fos protein. Fos protein is generally used as a marker for neuronal activity and has been linked to phosphorylation of… Expand
The LexA Protein from Deinococcus radiodurans Is Not Involvedin RecA Induction following γ Irradiation
Volume 183, no. 23, p. 6951–6956, 2001. Page 6953, column 2, line 9 from bottom: “RecA” should read “LexA.” Page 6953, column 2, line 8 from bottom: “LexA” should read “RecA.”
Cloning and characterization of uracil-DNA glycosylase and the biological consequences of the loss of its function in the nematode Caenorhabditis elegans.
Uracil arises in DNA from spontaneous deamination of cytosine and through incorporation of dUMP by DNA polymerase during DNA replication. Excision of uracil by the action of uracil-DNA glycosylase… Expand
Molecular analysis of the Deinococcus radiodurans recA locus and identification of a mutation site in a DNA repair-deficient mutant, rec30.
Deinococcus radiodurans strain rec30, which is a DNA damage repair-deficient mutant, has been estimated to be defective in the deinococcal recA gene. To identify the mutation site of strain rec30 and… Expand
The role of Deinococcus radiodurans RecFOR proteins in homologous recombination.
Deinococcus radiodurans exhibits extraordinary resistance to the lethal effect of DNA-damaging agents, a characteristic attributed to its highly proficient DNA repair capacity. Although the D.… Expand
Characterization and distribution of IS8301 in the radioresistant bacterium Deinococcus radiodurans.
The insertion sequence element IS8301 isolated from the radiation resistant bacterium Deinococcus radiodurans strain KD8301 was characterized. IS8301 is comprised of 1,736-bp, lacks terminal inverted… Expand