• Publications
  • Influence
Vildagliptin dose-dependently improves glycemic control in Japanese patients with type 2 diabetes mellitus.
TLDR
Vildagliptin 50mg bid was considered to be the most effective and well-tolerated dose, and therefore can be considered the recommended clinical dose for Japanese patients with T2DM.
Association between HbA1c variability and mortality in patients with type 2 diabetes.
TLDR
HbA 1c variability is a predictor of all-cause mortality, especially non-cancer mortality including CVD, in patients with type 2 diabetes, independent of mean HbA1c level, and might predict cancer mortality.
The effect of fasting plasma glucose variability on the risk of retinopathy in type 2 diabetic patients: retrospective long-term follow-up.
TLDR
In type 2 diabetic patients, FPG variability is a risk factor for diabetic retinopathy independent of the mean FPG or HbA1c.
Efficacy and tolerability of vildagliptin as an add-on to glimepiride in Japanese patients with Type 2 diabetes mellitus.
TLDR
Vildagliptin is effective and well tolerated as an add-on to glimepiride in Japanese patients with Type 2 diabetes mellitus who were inadequately controlled.
The effects of fasting plasma glucose variability and time-dependent glycemic control on the long-term risk of retinopathy in type 2 diabetic patients.
Long-term fasting plasma glucose (FPG) variability was a risk factor for proliferative diabetic retinopathy (PDR) independent of the mean FPG or HbA1c in people with type 2 diabetes. PDR development
Fasting tests of insulin secretion and sensitivity predict future prediabetes in Japanese with normal glucose tolerance
TLDR
This work investigated whether or not baseline measures of insulin secretion and sensitivity obtained from fasting blood specimens were related to the development of prediabetes and how these measures compared with those based on the OGTT.
Addition of mitiglinide to pioglitazone monotherapy improves overall glycemic control in Japanese patients with type 2 diabetes: a randomized double blind trial.
TLDR
HbA (1C) was significantly improved in the mitiglinide combination groups compared with the pioglitazone monotherapy group, and significantly more patients achieved HbA(1C), which effectively improves glycemic control in type 2 diabetic patients who are inadequately controlled by pioglenide monotherapy.
Effect of mitiglinide on glycemic control over 52 weeks in Japanese type 2 diabetic patients insufficiently controlled with pioglitazone monotherapy.
TLDR
In type 2 diabetic patients combination therapy with mitiglinide and pioglitazone exerted significant long-term improvements in HbA(1C), FPG, and PPG and was well tolerated.
[Risk factors for diabetic retinopathy].
  • M. Kikuchi
  • Medicine
    Nihon rinsho. Japanese journal of clinical…
  • 1 October 1997
Time-to-effect relationships between systolic blood pressure and the risks of nephropathy and retinopathy in patients with type 2 diabetes.
TLDR
Continuous SBP lowering is necessary to prevent nephropathy, whereas SBP control during the preceding 5years seems to be important to prevent retinopathy.
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