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Genome-wide CRISPR screen for Zika virus resistance in human neural cells
- Yun Li, J. Muffat, R. Jaenisch
- Biology, MedicineProceedings of the National Academy of Sciences
- 24 April 2019
Significance Zika virus (ZIKV) is a neurotropic and neurovirulent arbovirus that has severe detrimental impact on the developing human fetal brain. We used a genome-wide CRISPR-Cas9 knockout screen…
Comparative analysis of antioxidants against cadmium induced reproductive toxicity in adult male rats
- S. Jahan, M. Khan, Shakeel Ahmed, H. Ullah
- BiologySystems biology in reproductive medicine
- 15 January 2014
Findings suggest that Ficus religiosa and sulforaphane are more powerful antioxidants as compared to vitamin E in reversing the oxidative stress and can have a protective role against Cd induced reproductive toxicity in adult male rats.
Review of Haploidentical Hematopoietic Cell Transplantation
- M. Khan, Q. Bashir, Q. Chaudhry, P. Ahmed, T. Satti, S. K. Mahmood
- Medicine, BiologyJournal of global oncology
- 1 December 2018
As the experience with haplo-HCTs grows, the clinical outcomes are becoming more at par with those seen with fully matched unrelated donor allogeneic HCTs, including graft failure, infections, delayed immune reconstitution, and disease relapse.
Epidemiological, clinical and genetic characterization of aplastic anemia patients in Pakistan
It is suggested that epidemiologic and etiologic factors as well as host genetic predisposition exclusively or cooperatively trigger AA in Pakistan.
Graft versus host disease in allogeneic stem cell transplantation--3 1/2 years experience.
The morbidity and mortality due to severe acute and chronic GvHD remains high despite standard prophylaxis against Gv HD and new strategies are needed to prevent and treat Gvhd.
Autologous mesenchymal stromal cell transplantation for spinal cord injury: A Phase I pilot study.
Outcome of Fludarabine Based Conditioning in High Risk Aplastic Anemia Patients Undergoing Matched Related Donor Transplantation: A Single Center Study from Pakistan.
Nocardia canaliculitis presenting as pouted punctum.
A rare case of culture-positive Nocardia canaliculitis is reported that presented with a history of chronic conjunctivitis and epiphora for the last 1.4 years, refractory to multiple treatment…
Human Epididymis Protein 4 Promotes Events Associated with Metastatic Ovarian Cancer via Regulation of the Extracelluar Matrix
A direct role for HE4 in mediating malignant properties of ovarian cancer cells is found and the need for HE 4-targeted therapies that will suppress activation of oncogenic transcriptional activation and signaling cascades is validated.