M. Kepczynski

Publications60
h-index19
Citations994
Highly Influential Citations12
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Interaction of curcumin with lipid monolayers and liposomal bilayers.
Curcumin shows huge potential as an anticancer and anti-inflammatory agent. However, to achieve a satisfactory bioavailability and stability of this compound, its liposomal form is preferable. Our… Expand
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Which physical and structural factors of liposome carriers control their drug-loading efficiency?
The correlation between structural and physical properties of lipid membrane and its drug-loading efficiency were studied. The properties of bilayer were altered by incorporation of several lipidic… Expand
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Silicone nanocapsules templated inside the membranes of catanionic vesicles.
A simple and effective way to synthesize hollow silicone resin particles of controlled diameter is presented. The synthesis utilizes catanionic vesicles as templates for the… Expand
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Bilayer structures in dioctadecyldimethylammonium bromide/oleic acid dispersions.
This paper reports on the properties of bilayers composed of dioctadecyldimethylammonium bromide (DODAB) and oleic acid (OA) at various molar ratios. The mole fraction of OA, X(OA), was varied in the… Expand
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Lipid content in pig blastocysts cultured in the presence or absence of protein and vitamin E or phenazine ethosulfate.
In the present study, total lipid content and content of triglycerides, phospholipids and cholesterol were determined in pig blastocysts cultured in medium without protein, supplemented with bovine… Expand
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Silicone Nanocapsules from Catanionic Vesicle Templates
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Multiple excitatory actions of orexins upon thalamo-cortical neurons in dorsal lateral geniculate nucleus - implications for vision modulation by arousal
The orexinergic system of the lateral hypothalamus plays a crucial role in maintaining wakefulness and mediating arousal in a circadian time-dependent manner. Due to the extensive connections of… Expand
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Molecular Insight into Drug-Loading Capacity of PEG-PLGA Nanoparticles for Itraconazole.
Nanoparticles made of amphiphilic block copolymers comprising biodegradable core-forming blocks are very attractive for the preparation of drug-delivery systems with sustained release. Their… Expand
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Study of interaction between PEG carrier and three relevant drug molecules: piroxicam, paclitaxel, and hematoporphyrin.
Molecular dynamics simulation has been used to study the specific interactions between poly(ethylene glycol) (PEG) and three drug molecules for which PEG is used to aid delivery: paclitaxel and… Expand
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Interaction of hematoporphyrin with lipid membranes.
Natural or synthetic porphyrins are being used as photosensitizers in photodiagnosis (PD) and photodynamic therapy (PDT) of malignancies and some other diseases. Understanding the interactions… Expand
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