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Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation
TLDR
This complete mtDNA tree includes previously published as well as newly identified haplogroups, is easily navigable, will be continuously and regularly updated in the future, and is online available at http://www.phylotree.org. Expand
Defining the role of common variation in the genomic and biological architecture of adult human height
TLDR
The results indicate a genetic architecture for human height that is characterized by a very large but finite number of causal variants, including mTOR, osteoglycin and binding of hyaluronic acid. Expand
The effective mutation rate at Y chromosome short tandem repeats, with application to human population-divergence time.
TLDR
This value is used to estimate the times of the African Bantu expansion, the divergence of Polynesian populations (the Maoris, Cook Islanders, and Samoans), and the origin of Gypsy populations from Bulgaria. Expand
Hundreds of variants clustered in genomic loci and biological pathways affect human height
TLDR
It is shown that hundreds of genetic variants, in at least 180 loci, influence adult height, a highly heritable and classic polygenic trait, and indicates that GWA studies can identify large numbers of loci that implicate biologically relevant genes and pathways. Expand
Y-chromosomal diversity in Europe is clinal and influenced primarily by geography, rather than by language.
TLDR
These patterns retain a strong signal of expansion from the Near East but also suggest that the demographic history of Europe has been complex and influenced by other major population movements, as well as by linguistic and geographic heterogeneities and the effects of drift. Expand
IrisPlex: a sensitive DNA tool for accurate prediction of blue and brown eye colour in the absence of ancestry information.
TLDR
The IrisPlex eye colour prediction test represents one of the first steps forward in the creation of a fully individualised EVC prediction system for future use in forensic DNA intelligence. Expand
Characteristics and frequency of germline mutations at microsatellite loci from the human Y chromosome, as revealed by direct observation in father/son pairs.
TLDR
The data indicate that the general mutational mechanism of microsatellites is independent of recombination, and mutation rates and characteristics of human Y-chromosomal microsatellite loci are consistent with those of autosomal microSatellites. Expand
Denisova admixture and the first modern human dispersals into Southeast Asia and Oceania.
TLDR
The results indicate that Denisova gene flow occurred into the common ancestors of New Guineans, Australians, and Mamanwa but not into the ancestors of the Jehai and Onge and suggest that relatives of present-day East Asians were not in Southeast Asia when the DenisovaGene flow occurred. Expand
Mutability of Y-chromosomal microsatellites: rates, characteristics, molecular bases, and forensic implications.
TLDR
The 13 most mutable Y-STRs are analyzed in an independent sample set and empirically proved their suitability for distinguishing close and distantly related males, expected to revolutionize Y-chromosomal applications in forensic biology. Expand
Correlation between Genetic and Geographic Structure in Europe
TLDR
Although Affymetrix GeneChip 500K genotype data from 2,514 individuals belonging to 23 different subpopulations was investigated, the existing differences were characterized by a strong continent-wide correlation between geographic and genetic distance, which provided evidence for a spatial continuity of genetic diversity in Europe. Expand
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