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Antileukemia activity in the Osillatoriaceae: isolation of Debromoaplysiatoxin from Lyngbya.
Chloroform extracts of several seaweeds from Enewetak Atoll, Marshall Islands, display activity against P-388 lymphocytic mouse leukemia, and may be the dermatitis-producing substance in L. majuscula, the cause of "swimmers' itch" outbreaks in Hawaiian waters. Expand
Antineoplastic evaluation of Pacific basin marine algae.
Several specimens showed high antitumor activity in both systems, with some featuring a notable lack of toxicity. Expand
Isolation and characterization of the cardiotonic polypeptide anthopleurin-A from the sea anemone Anthopleura xanthogrammica.
A highly potent cardiotonic polypeptide, anthopleurin-A, was isolated from the sea anemone, Anthopleura xanthogrammica (Brandt), using solvent partition, gel permeation chromatography, andExpand
Anticancer activity of zoanthids and the associated toxin, palytoxin, against Ehrlich ascites tumor and P-388 lymphocytic leukemia in mice.
The toxic component, palytoxin, was effective in the control and cure of Ehrlich ascites at extremely low dosages using several different methods of administration and displayed marginal activity against P-388 lymphocytic leukemia. Expand
Antitumor Activity in Mice of Tentacles of Two Tropical Sea Annelids
Dialyzed extracts of one of these annelids, Lanice conchilega, show activity in the retentate after pronase digestion, suggesting that antitumor activity is associated with a nonprotein component of the crude tentacle extract. Expand
Purification of a potent antitumor agent from a Tahitian sea anemone and methods of administration. Studies with Ehrlich ascites tumor in mice.
An antitumor substance, stoichactin, was obtained from an aqueous alcoholic extract of the sea anemone, identified as most probably being Stoichactis kenti, using dialysis and gel permeationExpand
Cardiac stimulant action of extracts of coelenterates on rat atria.
Crude aqueous ethanol extracts of nine out of 12 species of anthozoans and the one scyphozoan examined showed varying degrees of positive inotropic and chronotropic effects on isolated rat atria.Expand