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Tumor Infiltrating PD1-Positive Lymphocytes and the Expression of PD-L1 Predict Poor Prognosis of Soft Tissue Sarcomas
Recently, the possibility of PD1 pathway-targeted therapy has been extensively studied in various human malignant tumors. However, no previous study has investigated their potential application for… Expand
Expression of DBC1 and SIRT1 Is Associated with Poor Prognosis of Gastric Carcinoma
Purpose: SIRT1 (silent mating-type information regulation 2 homologue 1) expression has been reported to predict poor survival in some cancers. We therefore investigated the expression levels of… Expand
Expression of MUC1, MUC2, MUC5AC and MUC6 in cholangiocarcinoma: prognostic impact.
Mucin is a high molecular weight glycoprotein that plays an important role to protect the gastrointestinal tract epithelium. However, in cancer cells and during cancer progression, the expression… Expand
Sarcomatoid carcinoma of the colon: a case report.
- J. Kim, W. Moon, M. Kang, M. J. Park, D. G. Lee
- Journal of Korean medical science
- 1 October 2001
Sarcomatoid carcinoma is a rare biphasic tumor characterized by a combination of malignant epithelial and mesenchymal cells. We report a rare case of sarcomatoid carcinoma of the colon. A 41-yr-old… Expand
Involvement of endoplasmic reticulum stress in myofibroblastic differentiation of lung fibroblasts.
- H. A. Baek, Do Sung Kim, +6 authors M. Chung
- Biology, Medicine
- American journal of respiratory cell and…
- 14 December 2012
Stress that impairs endoplasmic reticulum (ER) function leads to an accumulation of unfolded or misfolded proteins in the ER (ER stress) and triggers the unfolded protein response (UPR). Recent… Expand
Expression and role of SIRT1 in hepatocellular carcinoma.
Silent mating type information regulation 2 homolog 1 (SIRT1) is a multifaceted, nicotinamide adenine dinucleotide-dependent protein deacetylase with involvement in a wide variety of cellular… Expand
Discoidin domain receptor 1 is associated with poor prognosis of non-small cell lung carcinomas.
Discoidin domain receptors (DDRs) are a novel class of receptor tyrosine kinases that bind to several collagens and facilitate cell adhesion. DDR1 is involved in cancer invasion. However, very… Expand
Expression and prognostic significance of SIRT1 in ovarian epithelial tumours
Aims: Sirtuin1 (SIRT1) is a nicotinamide adenine dinucleotide‐dependent deacetylase. Recently, some studies have suggested that SIRT1 could be over‐expressed in breast, prostate and colon cancers and… Expand
SIRT1 Expression is Associated With Poor Prognosis of Diffuse Large B-Cell Lymphoma
- K. Jang, S. H. Hwang, +12 authors W. Moon
- The American journal of surgical pathology
- 1 October 2008
Sirtuin1 (SIRT1) is a nicotinamide adenine dinucleotide-dependent deacetylase. Recently, it is suggested that SIRT1 may be involved in the development of malignant tumors including mouse lymphoma.… Expand
Expression of the serum response factor in hepatocellular carcinoma: implications for epithelial-mesenchymal transition.
- M. Park, K. R. Kim, +7 authors W. Moon
- Biology, Medicine
- International journal of oncology
- 1 December 2007
The acquisition of a migratory and invasive phenotype by cells of epithelial origin is associated with a gain of mesenchymal characteristics concomitant with a loss of the epithelial phenotype, a… Expand