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TIMP-3 in Bruch's membrane: changes during aging and in age-related macular degeneration.
PURPOSE To assess the distribution, content, and function of tissue inhibitor of metalloproteinases (TIMP)-3 during aging in normal eyes for comparison with the levels observed in eyes withExpand
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A study of the ability of tissue plasminogen activator to diffuse into the subretinal space after intravitreal injection in rabbits.
PURPOSE Intravitreal injections of tissue plasminogen activator have been used to lyse fibrin from blood in the subretinal space, despite the lack of proof that tissue plasminogen activator canExpand
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Inhibition of experimental choroidal neovascularization by overexpression of tissue inhibitor of metalloproteinases-3 in retinal pigment epithelium cells.
PURPOSE To evaluate the feasibility of introducing exogenous tissue inhibitor of metalloproteinases-3 gene into the rat retinal pigment epithelium using hemagglutinating virus of Japan liposomes andExpand
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Analysis of extracellular matrix synthesis during wound healing of retinal pigment epithelial cells
To investigate changes in retinal pigment epithelial (RPE) cells during wound healing, we evaluated the deposition of newly synthesized extracellular matrix (ECM) over time during wound healing inExpand
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Indocyanine green facilitates removal of epiretinal and internal limiting membranes in myopic eyes with retinal detachment.
PURPOSE To describe the use of intravitreal indocyanine green as an aid to identifying epiretinal membranes and internal-limiting membranes during surgery for a retinal detachment resulting from aExpand
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Macular translocation with chorioscleral outfolding: an experimental study.
PURPOSE Macular translocation by chorioscleral infolding has been proposed as a surgical intervention for exudative age-related macular degeneration, but the surgery is unpredictable and can beExpand
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A rapid method for isolation of retinal pigment epithelial cells from rat eyeballs.
A new, simple method for isolating retinal pigment epithelial (RPE) cells from rat eyeballs was developed: incubation of the eyeballs in 0.1% proteinase K solution. This method yielded an average ofExpand
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Effect of Ca(2+)-free and Mg(2+)-free BSS Plus solution on the retinal pigment epithelium and retina in rabbits.
PURPOSE To determine whether intravitreal irrigation with Ca(2+)-free and Mg(2+)-free BSS Plus (Alcon Laboratory, Fort Worth, Texas) solution alters the adhesiveness between the retinal pigmentExpand
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A study for TUNEL assay as a method of detecting apoptotic cells.
最近, TdT-mediated digoxygenin (biotin)-dUTP nick end labeling (TUNEL) 法でアポトーシス細胞を同定した研究が数多く報告されるようになった. しかし, パラフィン包埋組織標本については感度や特異性の点で問題があり, その染色条件が十分に検討されているとはいえない. また, 細胞診標本への応用の報告は少ない.Expand
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