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- Publications
- Influence
Drusen proteome analysis: An approach to the etiology of age-related macular degeneration
- J. Crabb, M. Miyagi, +9 authors J. Hollyfield
- Biology, Medicine
- Proceedings of the National Academy of Sciences…
- 21 October 2002
Drusen are extracellular deposits that accumulate below the retinal pigment epithelium on Bruch's membrane and are risk factors for developing age-related macular degeneration (AMD). The progression… Expand
Semaphorin‐4A, an activator for T‐cell‐mediated immunity, suppresses angiogenesis via Plexin‐D1
- T. Toyofuku, M. Yabuki, +4 authors M. Hori
- Biology, Medicine
- The EMBO journal
- 7 March 2007
Originally identified as axon guidance molecules, semaphorins are now known to be widely expressed mediators that play significant roles in immune responses and organ morphogenesis. However, not much… Expand
Testing of semichronically implanted retinal prosthesis by suprachoroidal-transretinal stimulation in patients with retinitis pigmentosa.
- T. Fujikado, M. Kamei, +9 authors K. Nishida
- Medicine
- Investigative ophthalmology & visual science
- 1 June 2011
PURPOSE
To examine the safety and effectiveness of a retinal prosthesis that is implanted semichronically in two patients with advanced retinitis pigmentosa (RP).
METHODS
Two eyes of two patients… Expand
Chronic photo-oxidative stress and subsequent MCP-1 activation as causative factors for age-related macular degeneration
- M. Suzuki, M. Tsujikawa, +9 authors M. Kamei
- Medicine, Biology
- Journal of Cell Science
- 26 March 2012
Age-related macular degeneration (AMD) is the leading cause of blindness among the elderly in developed countries. Although pathogenic factors, such as oxidative stress, inflammation and genetics are… Expand
Oxidized phospholipids in the macula increase with age and in eyes with age-related macular degeneration
Purpose There is good evidence that oxidative stress is involved in the pathogenesis of age-related macular degeneration (AMD). Because AMD has risk factors and histopathology similar to with… Expand
The rck/p54 candidate proto-oncogene product is a 54-kilodalton D-E-A-D box protein differentially expressed in human and mouse tissues.
- Y. Akao, O. Marukawa, +4 authors Y. Tsujimoto
- Biology, Medicine
- Cancer research
- 1 August 1995
Expression of the RCK gene, which is a target gene on 11q23 of the t(11;14) (q23;q32) translocation in the B-cell lymphoma cell line RC-K8, was studied by Northern and Western blot analyses. The RCK… Expand
Evaluation of phosphenes elicited by extraocular stimulation in normals and by suprachoroidal-transretinal stimulation in patients with retinitis pigmentosa
- T. Fujikado, T. Morimoto, +8 authors Y. Tano
- Medicine
- Graefe's Archive for Clinical and Experimental…
- 7 March 2007
BackgroundTo determine the efficient parameters to evoke electrical phosphenes is essential for the development of a retinal prosthesis. We studied the efficient parameters in normal subjects and… Expand
Transretinal electrical stimulation by an intrascleral multichannel electrode array in rabbit eyes
- K. Nakauchi, T. Fujikado, +11 authors Y. Tano
- Materials Science, Medicine
- Graefe's Archive for Clinical and Experimental…
- 1 February 2005
BackgroundA new method of stimulating the retina electrically, called suprachoroidal transretinal stimulation (STS), was shown to be effective in eliciting electrically evoked cortical potentials… Expand
Intravitreal bevacizumab to treat iris neovascularization and neovascular glaucoma secondary to ischemic retinal diseases in 41 consecutive cases.
- T. Wakabayashi, Y. Oshima, +7 authors Y. Tano
- Medicine
- Ophthalmology
- 1 September 2008
PURPOSE
To evaluate the biologic efficacy of intravitreal bevacizumab (IVB) for iris neovascularization (INV) or neovascular glaucoma (NVG) in patients with ischemic retinal disorders.
DESIGN… Expand
Transretinal Electrical Stimulation with a Suprachoroidal Multichannel Electrode in Rabbit Eyes
- H. Sakaguchi, T. Fujikado, +10 authors Y. Tano
- Medicine
- Japanese Journal of Ophthalmology
- 1 May 2004
PurposeSeveral approaches for placing an electrode device for visual prosthesis have been previously proposed. In this study, we investigated if transretinal stimulation from the suprachoroidal space… Expand