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Desmoglein-1 regulates esophageal epithelial barrier function and immune responses in eosinophilic esophagitis
The desmosomal cadherin desmoglein-1 (DSG1) is an essential intercellular adhesion molecule that is altered in various human cutaneous disorders; however, its regulation and function in allergicExpand
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Local B cells and IgE production in the oesophageal mucosa in eosinophilic oesophagitis
Background: Eosinophilic oesophagitis (EO) is an emerging yet increasingly prevalent disorder characterised by a dense and selective eosinophilic infiltration of the oesophageal wall. While EO isExpand
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Abnormal response to stress and impaired NPS-induced hyperlocomotion, anxiolytic effect and corticosterone increase in mice lacking NPSR1
NPSR1 is a G protein coupled receptor expressed in multiple brain regions involved in modulation of stress. Central administration of NPS, the putative endogenous ligand of NPSR1, can induceExpand
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Esophageal IgG4 levels correlate with histopathologic and transcriptomic features in eosinophilic esophagitis
Recent data associate eosinophilic esophagitis (EoE) with IgG4 rather than IgE, but its significance and function have not been determined. Our aims were to measure esophageal IgG4 levels and toExpand
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