M. K. Mingler

Publications8
h-index4
Citations432
Highly Influential Citations23
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Desmoglein-1 regulates esophageal epithelial barrier function and immune responses in eosinophilic esophagitis
The desmosomal cadherin desmoglein-1 (DSG1) is an essential intercellular adhesion molecule that is altered in various human cutaneous disorders; however, its regulation and function in allergic… Expand
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Local B cells and IgE production in the oesophageal mucosa in eosinophilic oesophagitis
Background: Eosinophilic oesophagitis (EO) is an emerging yet increasingly prevalent disorder characterised by a dense and selective eosinophilic infiltration of the oesophageal wall. While EO is… Expand
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Abnormal response to stress and impaired NPS-induced hyperlocomotion, anxiolytic effect and corticosterone increase in mice lacking NPSR1
NPSR1 is a G protein coupled receptor expressed in multiple brain regions involved in modulation of stress. Central administration of NPS, the putative endogenous ligand of NPSR1, can induce… Expand
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Esophageal IgG4 levels correlate with histopathologic and transcriptomic features in eosinophilic esophagitis
Recent data associate eosinophilic esophagitis (EoE) with IgG4 rather than IgE, but its significance and function have not been determined. Our aims were to measure esophageal IgG4 levels and to… Expand
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IL-13 Transgene-Induced Experimental Eosinophilic Esophagitis (EE) is Associated with Increased Esophageal Circumference and Extensive Angiogenesis
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Esophageal IgG4 Levels Are Elevated in Pediatric Eosinophilic Esophagitis and Correlate with Esophageal Histopathology Including Levels of Eosinophils
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X chromosomal linkage to eosinophilic esophagitis susceptibility
Dissecting the Contributions of IL4 and IL13 to Allergen-Induced Diarrhea