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Reduced Anxiety, Conditioned Fear, and Hippocampal Long-Term Potentiation in Transient Receptor Potential Vanilloid Type 1 Receptor-Deficient Mice
These data provide first evidence for fear-promoting effects of TRPV1 with respect to both innate and conditioned fear and for a decisive role of this receptor in synaptic plasticity. Expand
A Targeted Deletion in α-Tectorin Reveals that the Tectorial Membrane Is Required for the Gain and Timing of Cochlear Feedback
Cochlear microphonics recorded in alpha-tectorin mutants differ in both phase and symmetry relative to those of wild-type mice, indicating that the tectorial membrane ensures that outer hair cells can effectively respond to basilar membrane motion and that feedback is delivered with the appropriate gain and timing required for amplification. Expand
Correlating Stimulus-Specific Adaptation of Cortical Neurons and Local Field Potentials in the Awake Rat
It is concluded that single neurons in the auditory cortex of the awake rat adapt in a stimulus-specific manner and contribute to corresponding changes in eLFP but do not generate a late deviant response component directly equivalent to the human MMN. Expand
Nonlinear mechanical responses of mouse cochlear hair bundles
The stiffness of sensory hair bundles of both inner (IHC) and outer (OHC) hair cells was measured with calibrated silica fibres in mouse cochlear cultures to test the hypothesis that the mechanicalExpand
Ambiguities in sound-duration selectivity by neurons in the inferior colliculus of the bat Molossus molossus from Cuba.
The range of best durations in the inferior colliculus of this species approximates the durations of their echolocation calls, suggesting that, as has been shown in other species of bats and frogs, the filter mechanism that produces duration tuning is selective for species-specific sounds relevant to behavior. Expand
Comparative aspects of cochlear functional organization in mammals
A comparison of the monotreme cochlea with that of marsupial and placental mammals highlights important evolutionary steps towards a hearing organ dedicated to process higher frequencies and a larger frequency range than found in non-mammalian vertebrates. Expand
The functional role of GABA and glycine in monaural and binaural processing in the inferior colliculus of horseshoe bats
Single unit recordings from the central nucleus of the inferior colliculus of horseshoe bats employing microiontophoresis of the putative neurotransmitters and their antagonists bicuculline and strychnine were studied, suggesting a differential supply by GABAergic and glycinergic networks. Expand
Development of echolocation calls in the mustached bat, Pteronotus parnellii.
The maturation of echolocation calls and the development of Doppler-shift compensation was studied in Cuba where large maternity colonies are found in hot caves, and young bats that were capable of very brief active flights but before the time of active foraging outside the cave emerged. Expand
The acoustic two-tone distortions 2f1-f2 and f2-f1 and their possible relation to changes in the operating point of the cochlear amplifier
To test this hypothesis, low-frequency tones were used to bias the position of the cochlear partition in the gerbil and phase-correlated changes of f2-f1 occurred at bias tone levels where there were almost no effects on 2f1-f2. Expand
Stimulus-Specific Adaptation in the Gerbil Primary Auditory Thalamus Is the Result of a Fast Frequency-Specific Habituation and Is Regulated by the Corticofugal System
A more general function of SSA is indicated in the processing and analysis of auditory information than the term novelty detection suggests, as recorded neuronal responses from the ventral part of the medial geniculate body indicated. Expand