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The effects of dexamethasone on fibronectin expression in cultured human trabecular meshwork cells.
- H. T. Steely, S. Browder, M. Julian, S. T. Miggans, K. Wilson, A. Clark
- Biology, Medicine
- Investigative ophthalmology & visual science
- 1 June 1992
Topical administration of glucocorticoids to the eye can lead to the development of ocular hypertension. This increase in intraocular pressure is caused by the heightened resistance to flow of… Expand
Aortic lathyrism and atheroma in the rat by prolonged hyperlipidic diet.
Constant, deep, extensive aortic atheroma can be induced in rats that are athero-resistant. Two main factors are involved in this experimentation: (1) Parietal alteration following chronic… Expand
Aortic lathyrism: ultrastructural study of lesions in the aortic wall and the protective effect of pyridinol carbamate.
Electron-microscopic examination of aortas of rat treated orally and chronically with β-aminopropionitrile (BAPN) has shown progressive lesions in the elastic framework. This is associated with… Expand
[Chronic lathyrism. Experimental model of the ageing of the connective tissue in man (author's transl)].
Fibroblast changes in cutaneous ageing
With ageing there are progressive modifications in the connective tissue of the dermis. In ten young subjects the collagenous bundles are thick and the fibroblasts are active cells in close contact… Expand
Chronic lathyrism and atheromatosis in the rat
- H. Bouissou, J. Thiers, L. Douste-Blazy, M. T. Pieraggi, M. Julian
- Biology, Medicine
- Virchows Archiv A
- 26 October 1978
Temporary chronic administration of Beta-amino-propionitrile (B.A.P.N.) produced morphological and biochemical changes of the aortic wall of rat as well as abnormalities of the plasma lipid levels. A… Expand
Identifying arteriosclerosis and aortic atheromatosis by skin biopsy.
Summary Photonic and ultrastructural examination of skin biopsies accurately reflect the condition of vascular walls. A normal skin type 0 is the equivalent of normal vessels, while skin types II and… Expand
Chronic lathyrism. Effect of beta aminopropionitrile on the aortic wall in the adult rat.
- M. Julian, M. T. Pieraggi, H. Bouissou
- Chemistry, Medicine
- Pharmacological research communications
- 1 June 1979
Summary BAPN did not have the same effect in weaning and adult rats. The BAPN was inactive on the aortic wall of adult rat but it induced clinical symptoms and severe aortic partietal lesions in the… Expand
Fine structural evidence of increased endothelial permeability in chronic lathyrism
The endothelium of the thoracic aorta of Wistar rats intoxicated with Beta-Aminopropionitrile (BAPN) for 9 weeks was studied. The animals were sacrificed at intervals, from the first to the 9th week… Expand
[Experimental lathyrism. Simultaneous changes in skin and aortic connective tissue].