• Publications
  • Influence
In Vitro Absorption and Metabolism of Nobiletin, a Chemopreventive Polymethoxyflavonoid in Citrus Fruits
It is suggested that PMFs including NOB have properties distinct from those of general flavonoids for absorption and metabolism in vitro, while that of LT did not. Expand
Studies on the inhibitory effects of some acridone alkaloids on Epstein-Barr virus activation.
Twenty-five acridone alkaloids from Citrus plants were examined for their inhibitory effects on Epstein-Barr virus activation by a short-term in vitro assay. 5-Hydroxynoracronycine (20) andExpand
A New Flavonoid and Other New Components from Citrus Plants
A new flavonoid, citflavanone (1), and prenylated phenol derivatives, etrogol (7) and valencic acid (8), were isolated from roots and root barks of Citrus natsudaidai (natsudaidai), C. medica (etrogExpand
Studies on the constituents of Yalaha. Structures of a new acridone alkaloid and two new coumarins
A new acridone alkaloid, 1, 3, 5-trihydroxy-10-methylacridone (8), and two new coumarins, trans-clausarinol (9) and khelmarin-D (11), were isolated from the root of Yalaha [several hybrid seedlingsExpand
[Chemical study of citrus plants in the search for cancer chemopreventive agents].
  • M. Ju-ichi
  • Chemistry, Medicine
  • Yakugaku zasshi : Journal of the Pharmaceutical…
  • 1 March 2005
3,5,6,7,8,3',4'-heptamethoxyflavone (HPT) has both antitumor promotion and initiation activities and is more effective than auraptene and nobiletin, which are potential candidates for effective multidrug resistance agents in cancer chemotherapy. Expand
Cancer chemopreventive activity of 3,5,6,7,8,3',4'-heptamethoxyflavone from the peel of citrus plants.
HPT exhibited the remarkable anti-tumor-initiating effect on mouse skin and it suggested the possibility of HPT being a chemopreventive agent against nitric oxide (NO) carcinogenesis. Expand
Isolation and Identification of Two New Flavanones and a Chalcone from Citrus kinokuni
Two new flavanones and one chalcone were isolated from the peel of Citrus kinokuni Hort. ex Tanaka and identified as (2S)-5,6,7,8,4'-pentamethoxyflavanone (1), (2S)-5,6,7,3',4'-pentamethoxyflavanoneExpand
Unique action of a modified weakly acidic uncoupler without an acidic group, methylated SF 6847, as an inhibitor of oxidative phosphorylation with no uncoupling activity: possible identity of
O-methylated SF 6847 is a unique inhibitor of oxidative phosphorylation, and the possible identity of the uncoupler binding protein is discussed on the basis of these results. Expand
New Coumarins from Citrus Plants
Four new coumarins, named peroxytamarin (1), cis-casegravol (5), citrusarin-A (7), and citrusarin-B (8), were isolated from root of Citrus plants and their structures were elucidated by chemical andExpand