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Pulmonary damage after intramedullary femoral nailing in traumatized sheep--is there an effect from different nailing methods?
Stabilization of femoral shaft fractures is a controversial issue in the management of patients with multiple trauma. Intramedullary nailing usually is preferred primarily; in recent years, however,Expand
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Topical 0.2% glyceryl trinitrate ointment for anal fissures: long‐term efficacy in routine clinical practice
Objective  Randomized controlled trials have reported fissure healing rates of 60–70% using topical 0.2% GTN ointment, but the effectiveness of this therapy in routine clinical practice, particularlyExpand
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Diltiazem Heals Glyceryl Trinitrate–Resistant Chronic Anal Fissures
AbstractPURPOSE: Both topical diltiazem, a calcium channel blocker, and glyceryl trinitrate, a nitric oxide donor, lower anal pressure and heal two-thirds of chronic anal fissures. This studyExpand
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A randomized trial of oralvs. topical diltiazem for chronic anal fissures
INTRODUCTION: Chemical sphincterotomy has proved effective in treating chronic anal fissure. Glyceryl trinitrate is the most widely used agent, and topical 0.2 percent glyceryl trinitrate ointmentExpand
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The role of topical diltiazem in the treatment of chronic anal fissures that have failed glyceryl trinitrate therapy
Objective  The treatment of anal fissures has evolved over the last 5 years with the development of topical treatments aimed at reducing sphincter hypertonia. This is thought to improve anal mucosalExpand
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Lateral internal sphincterotomy is not redundant in the era of glyceryl trinitrate therapy for chronic anal fissure
Lateral internal sphincterotomy has been the standard treatment for chronic anal fissure, but fissure healing rates of up to 80% with topical glyceryl trinitrate (GTN) treatment have suggested thatExpand
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Topical 0.2 percent glyceryl trinitrate ointment has a short-lived effect on resting anal pressure
PURPOSE: Glyceryl trinitrate ointment applied to the anal verge lowers anal resting pressure, but its duration of action is uncertain. This study investigated the effect and duration of action of 0.2Expand
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[Morbidity and mortality in para-articular femoral fractures in advanced age. Results of a prospective study].
UNLABELLED This study was designed to determine risk factors and individual dispositions associated with morbidity and mortality in the operative treatment of hip fractures in elderly patients. Expand
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Anal Fissure.
Anal fissure is a common condition, and although most are short-lived and heal spontaneously, those that persist and require intervention cause considerable morbidity in an otherwise healthy youngExpand
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Pharmacological characterization of neurogenic responses of the sheep isolated internal anal sphincter
The aim of the study was to establish the nature of the neurogenic responses of the sheep isolated anal sphincter. Isolated strips of sheep internal anal sphincter develop intrinsic contractile toneExpand
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