• Publications
  • Influence
Building neural representations of habits.
Large and widely distributed changes in the neuronal activity patterns occurred in the sensorimotor striatum during behavioral acquisition, culminating in task-related activity emphasizing the beginning and end of the automatized procedure. Expand
Fear of falling and postural control in Parkinson's disease
FOF was significantly associated with a qualitative estimate of postural control in PD; individuals with PD who had a greater degree of posture impairment reported greater FOF, and an estimate of FOF may help to explain quantitative postural instability in PD. Expand
An evaluation of sensorimotor integration during locomotion toward a target in Parkinson’s disease
The results suggest that the basal ganglia are not specifically involved in visuoproprioceptive integration; however, assimilation of proprioceptive feedback to guide an ongoing movement may be a critical function of the basal Ganglia. Expand
Spike source localization with tetrodes
The method uses a nonlinear mapping of a set of tetrode tip amplitudes into three-dimensional (3D) space, followed by a self-organizing map clustering technique, which performs better than tetrodes peak amplitudes and it is roughly equivalent with amplitude ratios. Expand
Chronic acquired hepatocerebral degeneration: Case reports and new insights
  • M. Jog, A. Lang
  • Medicine
  • Movement disorders : official journal of the…
  • 1 November 1995
Three cases of chronic acquired hepatocerebral degeneration are described with detailed clinical and radiological documentation and pathogenetic mechanisms are discussed, including deposition of manganese in the brain is postulated in patients with CAHD. Expand
An update on the diagnosis and treatment of Parkinson disease
Parkinson disease is the second most common neurodegenerative disorder after Alzheimer disease and occurs in 1%–2% of people over the age of 60 years, rising to 3.5% at age 85–89 years. Expand
A randomized clinical trial of high-dosage coenzyme Q10 in early Parkinson disease: no evidence of benefit.
Coenzyme Q10 was safe and well tolerated in this population, but showed no evidence of clinical benefit, and the study was terminated after a prespecified futility criterion was reached. Expand
Dopaminergic modulation of timing control and variability in the gait of Parkinson's disease
It is demonstrated that medicated PD patients had poorer timing control than patients withdrawn from medication and healthy participants when modulating timing to an external stimulus, and step length contributed to overall slowness in PD, while temporal characteristics of gait did not. Expand
Supplement 4: Canadian Guidelines on Parkinson's Disease
Loudness perception and speech intensity control in Parkinson's disease.
The results support a speech loudness perception deficit in PD involving an abnormal perception of externally generated and self-generated speech intensity. Expand