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Identification of novel universal housekeeping genes by statistical analysis of microarray data.
- S. Lee, M. Jo, Jungeun Lee, S. S. Koh, Soyoun Kim
- Biology, Medicine
- Journal of biochemistry and molecular biology
- 31 March 2007
Housekeeping genes are widely used as internal controls in a variety of study types, including real time RT-PCR, microarrays, Northern analysis and RNase protection assays. However, even commonly… Expand
Development of single-stranded DNA aptamers for specific Bisphenol a detection.
The development of reagents with high affinity and specificity to small molecules is crucial for the high-throughput detection of chemical compounds, such as toxicants or pollutants. Aptamers are… Expand
Aptamer sandwich-based carbon nanotube sensors for single-carbon-atomic-resolution detection of non-polar small molecular species.
A portable sensor platform for the detection of small molecular species is crucial for the on-site monitoring of environmental pollutants, food toxicants, and disease-related metabolites. However, it… Expand
Selection and elution of aptamers using nanoporous sol-gel arrays with integrated microheaters.
RNA and DNA aptamers that bind to target molecules with high specificity and affinity have been a focus of diagnostics and therapeutic research. These aptamers are obtained by SELEX (Systematic… Expand
Sol-gel derived nanoporous compositions for entrapping small molecules and their outlook toward aptamer screening.
This paper reports for the first time the application of sol-gel microarrays for immobilizing nonsoluble small chemicals (Bisphenol-A; BPA). Also, known problems of sol-gel adhesion to conventional… Expand
Aptamer microarray mediated capture and mass spectrometry identification of biomarker in serum samples.
Sensitive detection of molecular biomarkers in clinical samples is crucially important in disease diagnostics. This paper reports the development of an aptamer microarray platform combined with… Expand
A sol-gel-based microfluidics system enhances the efficiency of RNA aptamer selection.
RNA and DNA aptamers that bind to target molecules with high specificity and affinity have been a focus of diagnostics and therapeutic research. These aptamers are obtained by SELEX often requiring… Expand
Evaluation of Novel Multiplex Antibody Kit for Human Immunodeficiency Virus 1/2 and Hepatitis C Virus Using Sol-Gel Based Microarray
Background. Microarrays enable high-throughput screening (HTS) of disease-related molecules, including important signaling proteins/peptides and small molecules that are in low abundance. In this… Expand
Multiplex selection and elution of aptamers using nanoporous sol-gel droplets and a microheater array
Multiplex in vitro selection of aptamers using nanoporous sol-gel arrays with integrated microheaters
Aptamers have emerged as alternative protein capture reagents that, like antibodies, show high affinity and specificity for their targets. Aptamers often have affinities in the picomolar to low… Expand