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Suppression of spontaneous dermatitis in NC/Nga murine model by PG102 isolated from Actinidia arguta.
TLDR
PG102T or PG102E administration significantly reduced dermatitis severity as well as scratching tendency in conventional mice and Histological findings indicated that the thickening of epidermis/dermis and the dermal infiltration of inflammatory cells including mast cells were greatly inhibited.
Therapeutic effects of PG201, an ethanol extract from herbs, through cartilage protection on collagenase-induced arthritis in rabbits.
TLDR
PG201 indeed has great potential as a form of treatment for osteoarthritis, and the results indicate that PG201 has therapeutic effects on CNIA through the prominent protection of cartilage.
Gastroprokinetic effects of DA-9701, a new prokinetic agent formulated with Pharbitis Semen and Corydalis Tuber.
TLDR
DA-9701 has potential as a safe and effective therapeutic for FD patients with abnormalities in GI motor function and drastically increased the gastric accommodation in Beagle dogs, shifting the pressure-volume curve toward considerably higher volume.
Control of IgE and selective T(H)1 and T(H)2 cytokines by PG102 isolated from Actinidia arguta.
TLDR
PG102T and PG102E have great potential as orally active immune modulators for the therapy of various allergic diseases.
Effects of Korean red ginseng (Panax Ginseng Meyer) on bisphenol A exposure and gynecologic complaints: single blind, randomized clinical trial of efficacy and safety
TLDR
Korean red ginseng is efficient for protection for female QOL and BPA- exposure and – related oxidative stress and individual variation in susceptibility to KRG should be further considered for identifying ideal therapy.
TNF-α increases lipogenesis via JNK and PI3K/Akt pathways in SZ95 human sebocytes.
TLDR
TNF-α induces lipogenesis in SZ95 human sebocytes through the JNK and phosphoinositide-3-kinase/Akt pathways and will be valuable in developing therapeutic strategies for control of seborrhea and acne.
Ergosterol peroxide from Chaga mushroom (Inonotus obliquus) exhibits anti-cancer activity by down-regulation of the β-catenin pathway in colorectal cancer.
TLDR
The data suggest that ergosterol peroxide suppresses the proliferation of CRC cell lines and effectively inhibits colitis-associated colon cancer in AOM/DSS-treated mice and advocate its use as a supplement in colon cancer chemoprevention.
A water-soluble extract from Cucurbita moschata shows anti-obesity effects by controlling lipid metabolism in a high fat diet-induced obesity mouse model.
TLDR
The data suggest that PG105 may have great potential as a novel anti-obesity agent in that both inhibition of lipid synthesis and acceleration of fatty acid breakdown are induced by this reagent.
Suppressive effects of PG201, an ethanol extract from herbs, on collagen-induced arthritis in mice.
TLDR
Administration of PG201 significantly suppressed the progression of CIA and inhibited the production of TNF-alpha and IL-1beta in the paws, indicating PG201 is a potential therapy for rheumatoid arthritis.
Pheophytin a and chlorophyll a suppress neuroinflammatory responses in lipopolysaccharide and interferon-γ-stimulated BV2 microglia.
TLDR
PP and CP may suppress inflammatory responses by inhibiting NF-κB activation and type I IFN signaling pathway and suggested that PP and CP have potential as anti-inflammatory agents for microglia-mediated neuroinflammatory disorders.
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