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SAP controls T cell responses to virus and terminal differentiation of TH2 cells
SH2D1A, which encodes signaling lymphocyte activation molecule (SLAM)–associated protein (SAP), is altered in patients with X-linked lymphoproliferative disease (XLP), a primary immunodeficiency.Expand
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Defective B cell responses in the absence of SH2D1A.
More than half of patients with X-linked lympho-proliferative disease, which is caused by a defect in the intracellular adapter protein SH2D1A, suffer from an extreme susceptibility to Epstein-BarrExpand
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Essential role of phosphoinositide 3‐kinase gamma in eosinophil chemotaxis within acute pulmonary inflammation
We and others have established an important role for phosphoinositide‐3 kinase gamma (PI3Kγ) in the chemotactic responses of macrophages and neutrophils. The involvement of this lipid kinase inExpand
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A Systematic Survey of Online Data Mining Technology Intended for Law Enforcement
TLDR
We present a systematic mapping study describing online data-mining literature which visibly targets law enforcement applications. Expand
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Infrasound tremor from bubble burst eruptions in the viscous shallow crater lake of White Island, New Zealand, and its implications for interpreting volcanic source processes
Abstract White Island volcano, New Zealand, produced two periods (January–February and July 2013) of episodic and persistent eruptions through a viscous shallow mud/sulphur pool. The eruptionsExpand
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Data exfiltration: A review of external attack vectors and countermeasures
TLDR
This paper is aimed at identifying and critically analysing data exfiltration attack vectors and countermeasures for reporting the status of the art and determining gaps for future research. Expand
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Evolution of a small hydrothermal eruption episode through a mud pool of varying depth and rheology, White Island, NZ
White Island volcano, New Zealand was a host to multiple hydrothermal eruptive episodes within a mud-sulphur pool in 2013. Although hydrothermal activity is common at White Island, past events haveExpand
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The configuration of built space at Pataraya and Wari provincial administration in Nasca
Abstract This paper uses access analysis to describe and analyze a system of regulated and hierarchical communication within the small Wari enclosure at the site of Pataraya—located near Nasca,Expand
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Discovering "Unknown Known" Security Requirements
TLDR
We present an approach to discover unknown knowns through multi-incident analysis to identify revisions to theoretical security models underpinning security requirements. Expand
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IL-1α mediates cellular cross-talk in the airway epithelial mesenchymal trophic unit
ABSTRACT The bronchial epithelium and underlying fibroblasts form an epithelial mesenchymal trophic unit (EMTU) which controls the airway microenvironment. We hypothesized that cell-cellExpand
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