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Fast and simultaneous analysis of biothiols by high-performance liquid chromatography with fluorescence detection under hydrophilic interaction chromatography conditions.
TLDR
The method could successfully quantify six thiols in a human plasma sample, while cysteamine could not be detected, and should be a useful tool for investigating the relationship between sulfur metabolism and related diseases.
Recent advances in hydrophilic interaction chromatography for quantitative analysis of endogenous and pharmaceutical compounds in plasma samples.
TLDR
Recent applications of HILIC for the analysis of endogenous and pharmaceutical compounds in plasma samples are reviewed and a discussion of column selection, sample pretreatment for HIL IC analysis, and detection sensitivity is provided.
Fast and quantitative analysis of branched-chain amino acids in biological samples using a pillar array column
TLDR
The method was used for the analysis of sports drink and human plasma samples and showed good agreements with those determined using a conventional high-performance liquid chromatography system, showing that the developed method could be a potential diagnostic tool in clinical research.
Liquid Chromatography Chip with Low-Dispersion and Low-Pressure-Drop Turn Structure Utilizing a Distribution-Controlled Pillar Array.
TLDR
A novel turn with low-dispersion and low-pressure-drop properties was developed, designed as a constant-radius turn filled with octagonal pillars that were arranged to control the linear velocity of the mobile phase in the radial direction.
HPLC-fluorescence determination of thiol compounds in the serum of human male and female subjects using HILIC-mode column.
TLDR
High-performance liquid chromatography-fluorescence detection using a hydrophilic interaction Chromatography-mode column (ZIC®-HILIC) was used to determine four kinds of thiol compounds in human serum, which were significantly higher than those of the female subjects.
Quantification of Biological Thiols in the Plasma of a Homocystinuria Model with Cystathionine β-Synthase Deficiency Utilizing Hydrophilic Interaction Liquid Chromatography and Fluorescence Detection
TLDR
The results indicated that biological thiols other than Hcy could also be utilized for the evaluation and investigation of homocystinuria pathologies.
Protein Deficiency-Induced Behavioral Abnormalities and Neurotransmitter Loss in Aged Mice Are Ameliorated by Essential Amino Acids
TLDR
The findings suggest the importance of dietary protein and essential amino acids for maintaining brain function and the mechanism by which dietary intake of protein affects memory and brain conditions is studied.
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