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Separation of Leucas aspera, a medicinal plant of Bangladesh, guided by prostaglandin inhibitory and antioxidant activities.
According to the traditional usage of the plant for antiinflammation and analgesia, Leucas aspera was tested for its prostaglandin (PG) inhibitory and antioxidant activities. The extract showed bothExpand
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Antioxidant, antinociceptive activity and general toxicity study of Dendrophthoe falcata and isolation of quercitrin as the major component
Plants have been used in traditional medicinal system for centuries. Bangladeshi medicinal plants have received considerable attention from the researchers for evaluation of their bioactivity. As aExpand
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Analgesic components of saposhnikovia root (Saposhnikovia divaricata).
By activity-oriented separation using the writhing method in mice, the analgesic components of Saposhnikovia root (Saposhnikovia divaricata Schischkin; Umbelliferae) were identified to be chromones,Expand
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Immunomodulatory constituents from an Ascomycete, Chaetomium seminudum.
A screening study focusing on immunomodulatory activity of the EtOAc extract of an Ascomycete, Chaetomium seminudum, has afforded a known epipolythiodioxopiperazine, chetomin (1), together with threeExpand
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Lignan glycosides and flavonoids from Saraca asoca with antioxidant activity
Five lignan glycosides, lyoniside, nudiposide, 5-methoxy-9-β-xylopyranosyl-(−)-isolariciresinol, icariside E3, and schizandriside, and three flavonoids, (−)-epicatechin,Expand
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Chromomycins A2 and A3 from Marine Actinomycetes with TRAIL Resistance-Overcoming and Wnt Signal Inhibitory Activities
A biological screening study of an actinomycetes strain assembly was conducted using a cell-based cytotoxicity assay. The CKK1019 strain was isolated from a sea sand sample. Cytotoxicity-guidedExpand
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Naturally Occurring Small‐Molecule Inhibitors of Hedgehog/GLI‐Mediated Transcription
The aberrant hedgehog (Hh)/GLI signaling pathway causes the formation and progression of a variety of tumors. To search for Hh/GLI inhibitors, we screened for naturally occurring inhibitors of theExpand
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Hyrtiosins A and B, new indole alkaloids from the Okinawan marine sponge Hyrtios erecta
Abstract Two new indole alkaloids, hyrtiosins A (2) and B (3), together with known 5-hydroxyindole-3-aldehyde (1) have been isolated from the Okinawan marine sponge Hyrtios erecta and theirExpand
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Stelliferins A–F, new antineoplastic isomalabaricane triterpenes from the Okinawan marine sponge Jaspis stellifera.
Abstract Six new antineoplastic isomalabaricane-type triterpenes, stelliferins A–F, have been isolated from the Okinawan marine sponge Jaspis stellifera . The structures were established byExpand
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