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Increased Production of Bioactive Lysophosphatidic Acid by Serum Lysophospholipase D in Human Pregnancy1
Abstract Lysophosphatidic acid (LPA) is a prototype of the lysophospholipid mediator family and has multiple effects in the female reproductive system. Although several metabolic routes have beenExpand
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Postmenopausal changes in production of type 1 and type 2 cytokines and the effects of hormone replacement therapy
ObjectiveAn appropriate defense against infective agents or malignant cells is attributed to the exquisitely balanced T helper 1 type (cellular) and T helper 2 type (humoral) immune reactions. WeExpand
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Expression of IL-17 mRNA in ovarian cancer.
IL-17 is considered as a proinflammatory cytokine. We have demonstrated IL-17 is an angiogenic factor and promotes tumor growth in murine tumor models. In this report, we investigated the expressionExpand
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A repertoire of cytokines in human seminal plasma.
The pathophysiological significance of seminal cytokines in sperm function is still controversial. We determined the repertoire of cytokines in seminal plasma obtained from men with or withoutExpand
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Increase of mouse leptin production by adipose tissue after midpregnancy: gestational profile of serum leptin concentration.
The serum concentration of leptin in 10 week old virgin ICR mice assessed by RIA was 1.70 +/- 0.08 ng/ml. The serum leptin concentration in the pregnant mice mated at 10 weeks of age significantlyExpand
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Changes in serum cytokine concentrations during the menopausal transition.
OBJECTIVE The purpose of the present study was to clarify the changes in serum concentrations of 17 cytokines in healthy women during the menopausal transition by using a multiplexed cytokine assayExpand
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Effect of insulin-like growth factor I on gonadotropin release from the hypothalamus-pituitary axis in vitro.
The effects of insulin-like growth factor-I on gonadotropin release were studied using primary culture of rat anterior pituitary cells incubated with IGF-I (20-5000 micrograms/l) and aExpand
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Circulating profiles of osteoprotegerin and soluble receptor activator of nuclear factor κB ligand in post-menopausal women
Objective: The aim of this study was to elucidate the detail profiles of circulating osteoprotegerin (OPG) and soluble receptor activator of nuclear factor κB ligand (sRANKL) in post-menopausalExpand
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Biological Effects of Hormone Replacement Therapy in Relation to Serum Estradiol Levels
Objective: Tissues in various parts of the body have different sensitivities to estradiol. However, it is very difficult to measure the serum estradiol levels precisely in women receiving oralExpand
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Effect of semen characteristics on pregnancy rate following intrauterine insemination.
OBJECTIVE To assess the effects of semen characteristics on the success of intrauterine insemination (IUI). DESIGN A retrospective study. SETTINGS The Department of Obstetrics and Gynecology,Expand
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