• Publications
  • Influence
Role of SUMO-interacting motif in Daxx SUMO modification, subnuclear localization, and repression of sumoylated transcription factors.
Small ubiquitin-like modifier (SUMO) modification has emerged as an important posttranslational control of protein functions. Daxx, a transcriptional corepressor, was reported to repress theExpand
  • 376
  • 33
Derivation of class II force fields. I. Methodology and quantum force field for the alkyl functional group and alkane molecules
TLDR
A new method for deriving force fields for molecular simulations has been developed. Expand
  • 572
  • 11
Mutations at KFRDI and VGK domains of enterovirus 71 3C protease affect its RNA binding and proteolytic activities.
The 3C protease (3C(pro)) of enterovirus 71 (EV71) is a good molecular target for drug discovery. Notably, this protease was found to possess RNA-binding activity. The regions responsible for RNAExpand
  • 49
  • 7
The Role of Apoptosis Signal-regulating Kinase 1 in Lymphotoxin-β Receptor-mediated Cell Death*
LIGHT (homologous tolymphotoxins, shows inducible expression, and competes with herpes simplex virus glycoprotein D forherpesvirus entry mediator, a receptor expressed byT lymphocytes) is a member ofExpand
  • 56
  • 5
Derivation of Class II Force Fields. III. Characterization of a Quantum Force Field for Alkanes
Recently, a quantum mechanical Class II force field (QMFF) was derived from a fit of HF/6–31G* ab initio energy and energy derivative data for alkanes, and a comparison of this quantum force fieldExpand
  • 74
  • 4
Protein Kinase C Inhibits Type VI Adenylyl Cyclase by Phosphorylating the Regulatory N Domain and Two Catalytic C1 and C2 Domains*
We previously showed that phosphorylation of Ser10 of the N terminus domain of the type VI adenylyl cyclase (ACVI) partly mediated protein kinase C (PKC)-induced inhibition of ACVI. We now reportExpand
  • 39
  • 4
Network position of hosts in food webs and their parasite diversity
Parasites are ubiquitous in ecological communities but it is only recently that they have been routinely included in food web studies. Using recently published data and the tool of network analysis,Expand
  • 71
  • 4
  • PDF
Topological and organizational properties of the products of house-keeping and tissue-specific genes in protein-protein interaction networks
TLDR
We analyzed the topological properties of proteins encoded by house-keeping genes and tissue-specific genes and their local connectivity structure in protein-protein interaction networks for a variety of human tissues. Expand
  • 40
  • 3
LISE: a server using ligand-interacting and site-enriched protein triangles for prediction of ligand-binding sites
TLDR
LISE is a web server for a novel method for predicting small molecule binding sites on proteins. Expand
  • 13
  • 3
  • PDF