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Compliance with mandatory reporting of clinical trial results on ClinicalTrials.gov: cross sectional study
Objective To examine compliance with mandatory reporting of summary clinical trial results (within one year of completion of trial) on ClinicalTrials.gov for studies that fall under the recent Food… Expand
Is there a causal relationship between the hypoxia-ischaemia associated with cardiorespiratory arrest and subdural haematomas? An observational study.
The aim of this study was to determine the frequency of subdural haematomas (SDHs) occurring in infants presenting following atraumatic cardiorespiratory collapse. This study was a review of… Expand
Interventions for the eradication of meticillin-resistant Staphylococcus aureus (MRSA) in people with cystic fibrosis.
- D. Lo, M. Hurley, M. Muhlebach, A. Smyth
- The Cochrane database of systematic reviews
- 24 February 2015
BACKGROUND Cystic fibrosis is an inherited recessive disorder of chloride transport that is characterised by recurrent and persistent pulmonary infections from resistant organisms that result in lung… Expand
Staphylococcus aureus in cystic fibrosis: pivotal role or bit part actor?
Purpose of review The cystic fibrosis (CF) lung has long been appreciated as a competitive niche for complex interactions between bacterial species. The individual relationships between effects on… Expand
Bronchopulmonary Dysplasia Within and Beyond the Neonatal Unit.
- Renu Khetan, M. Hurley, S. Spencer, J. Bhatt
- Advances in neonatal care : official journal of…
Background: Bronchopulmonary dysplasia (BPD), also known as chronic lung disease of prematurity or chronic neonatal lung disease, is a major cause of respiratory illness in premature babies. Newborn… Expand
Novel approaches to the treatment of Pseudomonas aeruginosa infections in cystic fibrosis
Pseudomonas aeruginosa chronically infects patients with cystic fibrosis and is associated with greater morbidity. There has been limited progress on the clinical development of new antibiotics with… Expand
The top 10 research priorities in cystic fibrosis developed by a partnership between people with CF and healthcare providers
There remain many treatment uncertainties in cystic fibrosis (CF). With limited resources, research should focus on questions which are most important to the CF community. We conducted a James Lind… Expand
Rate of improvement of CF life expectancy exceeds that of general population—Observational death registration study☆☆☆
- M. Hurley, T. McKeever, Andrew P Prayle, A. Fogarty, A. Smyth
- Journal of cystic fibrosis : official journal of…
- 1 July 2014
Background It is unclear why cystic fibrosis (CF) survival has improved. We wished to quantify increases in CF median age of death in the context of general population survival improvement. Method… Expand
Intravenous antibiotics for pulmonary exacerbations in people with cystic fibrosis.
BACKGROUND Cystic fibrosis is a multi-system disease characterised by the production of thick secretions causing recurrent pulmonary infection, often with unusual bacteria. Intravenous antibiotics… Expand
Early Respiratory Bacterial Detection and Antistaphylococcal Antibiotic Prophylaxis in Young Children with Cystic Fibrosis
- M. Hurley, A. Fogarty, T. McKeever, C. Goss, M. Rosenfeld, A. Smyth
- Annals of the American Thoracic Society
Rationale: Consensus is lacking regarding antistaphylococcal antibiotic prophylaxis use for young children with cystic fibrosis. Prophylaxis is recommended in the United Kingdom, but it is… Expand