M. Humar

Publications104
h-index30
Citations2,890
Highly Influential Citations38
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Volatile Anesthetics Induce Caspase-dependent, Mitochondria-mediated Apoptosis in Human T Lymphocytes In Vitro
TLDR
Neither anti-Fas/CD95 receptor antagonism nor FADD deficiency or caspase-8 deficiency were able to attenuate sevoflurane-mediated apoptosis, but independently of death receptor signaling.
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3D microlasers from self-assembled cholesteric liquid-crystal microdroplets.
TLDR
A tunable and omnidirectional microlaser in the form of a microdroplet of a dye-doped, cholesteric liquid crystal in a carrier fluid is demonstrated.
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Step‐Index Optical Fiber Made of Biocompatible Hydrogels
A biocompatible step-index optical fiber made of poly(ethylene glycol) and alginate hydrogels is demonstrated. The fabricated fiber exhibits excellent light-guiding efficiency in biological tissues.…
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Heme Oxygenase-1 Induction by the Clinically Used Anesthetic Isoflurane Protects Rat Livers From Ischemia/Reperfusion Injury
TLDR
This study provides first evidence that pretreatment with the nontoxic and clinically approved anesthetic isoflurane induces hepatic HO-1 expression, and thereby protects rat livers from ischemia/reperfusion injury.
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The mitogen-activated protein kinase p38 regulates activator protein 1 by direct phosphorylation of c-Jun.
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Intracellular microlasers
TLDR
Two distinct types of microresonators are explored: soft and hard, that support whispering-gallery modes (WGM) and WGMs within phagocytized polystyrene beads of different sizes that enable individual tagging of thousands of cells easily and, in principle, a much larger number by multiplexing with different dyes.
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Bioabsorbable polymer optical waveguides for deep-tissue photomedicine
TLDR
In contrast to conventional optical fibres, which must be removed from the body soon after use, the biodegradable and biocompatible waveguides may be used for long-term light delivery and need not be removed as they are gradually resorbed by the tissue.
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Inhibition of Activator Protein 1 by Barbiturates Is Mediated by Differential Effects on Mitogen-Activated Protein Kinases and the Small G Proteins Ras and Rac-1
TLDR
The results contribute to the explanation of a clinically manifested immune suppression in barbiturate-treated patients and support the idea of a MAP kinase-independent regulation of AP-1 by PKC and calcium in human T cells.
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Thiopental inhibits the activation of nuclear factor kappaB.
TLDR
Thiopental inhibits the activation of NF-kappaB and may provide a molecular mechanism for some of the immunosuppressing effects associated with thiopental therapy.
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Thiopental Inhibits the Activation of Nuclear Factor &kgr;B
TLDR
Thiopental inhibits the activation of NF-&kgr;B and may provide a molecular mechanism for some of the immunosuppressing effects associated with thiopental therapy, as demonstrated in human T lymphocytes in vitro.
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