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Abdominal vagal mediation of the satiety effects of CCK in rats.
CCK type 1 (CCK1) receptor antagonists differing in blood-brain barrier permeability were used to test the hypothesis that satiety is mediated in part by CCK action at CCK1 receptors on vagal sensoryExpand
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Effects of peripheral CCK receptor blockade on feeding responses to duodenal nutrient infusions in rats.
Type A cholecystokinin receptor (CCKAR) antagonists differing in blood-brain barrier permeability were used to test the hypothesis that duodenal delivery of protein, carbohydrate, and fat producesExpand
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Effects of peripheral CCK receptor blockade on food intake in rats.
Type A cholecystokinin receptor (CCKAR) antagonists differing in blood-brain barrier permeability were used to test the hypothesis that satiety is mediated, in part, by CCK action at CCKARs locatedExpand
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Relative Blood‐brain Barrier Permeabilities of the Cholecystokinin Receptor Antagonists Devazepide and A‐65186 in Rats
The blood‐brain barrier permeabilities of the type‐A cholecystokinin receptor antagonists devazepide and A‐65186 (Nα‐3‐quinolinoyl‐D‐Glu‐N,N‐dipentylamide) have been compared with those of theExpand
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Modifications to the N-terminus but not the C-terminus of calcitonin gene-related peptide(8-37) produce antagonists with increased affinity.
Seventeen novel analogues of human calcitonin gene-related peptide(8-37) (hCGRP(8-37)) were synthesized by solid-phase methods and purified to apparent homogeneity by semipreparative cation exchangeExpand
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Pharmacological Characterization of Novel α-Calcitonin Gene-Related Peptide (CGRP) Receptor Peptide Antagonists That Are Selective for Human CGRP Receptors
Human α-calcitonin gene-related peptide (CGRP) is a 37-residue neuropeptide that produces a variety of cardiovascular and other effects via activation of specific CGRP receptors that produce cAMP.Expand
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Effects of peripheral CCK receptor blockade on gastric emptying in rats.
Type A CCK receptor (CCKAR) antagonists differing in blood-brain barrier permeability [devazepide penetrates; the dicyclohexylammonium salt of Nalpha-3-quinolinoyl-d-Glu-N,N-dipentylamide (A-70104)Expand
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Tandem Vicinal Difunctionalization: β‐Addition to α,β‐Unsaturated Carbonyl Substrates Followed by α‐Functionalization
Vicinal difunctionalization reactions play an important role in modern synthetic organic chemistry. They provide access to complex structures in a stereocontrolled fashion and act as powerful,Expand
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Organic-Solvent-Free Phase-Transfer Oxidation of Alcohols Using Hydrogen Peroxide
Organic-solvent-free oxidations of alcohols using aqueous hydrogen peroxide in the presence of sodium tungstate and phase-transfer catalysts provide a general, safe, simple, and cost-effective meansExpand
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