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High-Quality Binary Protein Interaction Map of the Yeast Interactome Network
A comparative quality assessment of current yeast interactome data sets is carried out, demonstrating that high-throughput yeast two-hybrid (Y2H) screening provides high-quality binary interaction information. Expand
The SapB morphogen is a lantibiotic-like peptide derived from the product of the developmental gene ramS in Streptomyces coelicolor.
- S. Kodani, M. Hudson, M. Durrant, M. Buttner, J. Nodwell, J. Willey
- Biology, Medicine
- Proceedings of the National Academy of Sciences…
- 3 August 2004
It is concluded that SapB is derived from RamS through proteolytic cleavage and the introduction of four dehydroalanine residues and two lanthionine bridges, providing an example of a morphogenetic role for an antibiotic-like molecule. Expand
Identification of differentially expressed proteins in ovarian cancer using high-density protein microarrays
- M. Hudson, I. Pozdnyakova, K. Haines, G. Mor, M. Snyder
- Biology, Medicine
- Proceedings of the National Academy of Sciences
- 30 October 2007
Overall these studies identified candidate tissue marker proteins for ovarian cancer and demonstrate that protein microarrays provide a powerful approach to identify proteins aberrantly expressed in disease states. Expand
High-throughput methods of regulatory element discovery.
Three basic methods for identifying regions of protein-DNA interaction will be introduced and complementary methods of exploring protein- DNA interactions will increase the fundamental knowledge of how the information contained within the genome sequence is accessed and processed. Expand
Membrane association and kinase-like motifs of the RamC protein of Streptomyces coelicolor.
The protein RamC is required for the production of the spore-forming cells called aerial hyphae by the filamentous bacterium Streptomyces coelicolor and it is shown that protein kinase-like sequence motifs in the amino-terminal half of the protein are required for function in vivo. Expand
Dimerization of the RamC morphogenetic protein of Streptomyces coelicolor.
The presence of multiple copies of a defective allele of ramC inhibits morphogenesis in S. coelicolor, consistent with either titration of a target or formation of inactive RamC multimers, and data suggest that RamC acts as a dimer in vivo. Expand
The Upper Green River Barcode of Life Project
A DNA barcoding exercise for first year “Undergraduate Experience” students in which participants catch arthropods from the authors' university field station, the Upper Green River Biological Preserve, and produces 28 arthropod barcodes, which will be augmented by the work of future classes. Expand
Comparative ultrastructure of spermatozoa from two regular and two irregular New Zealand echinoids
Spermatozoa from four species of echinoid found in New Zealand had morphological characteristics typical of other echinoids, including a conical sperm head with an acrosome-capped nucleus, a midpiece, and a single long flagellum, reflecting the membership of the former two populations in a distinct Pacific clade. Expand
Implant device core-shell having an inner core lobe
- M. Hudson
- Materials Science
- 29 June 2011
An implant device comprising: a. an outer sheath comprising a biocompatible polymer and having a longitudinal surface of the sheath uncovered and exposed distal and proximal end surfaces; and b. an… Expand
Sperm performance and fertilisation in the sea urchin Evechinus chloroticus under increasing pCO2
- M. Hudson
This study shows OA is impacting E. chloroticus sperm performance and regulation of pHi in a non-linear way andVariability in performance of sperm and FS response to OA indicate the possible adaptive potential to Oa, with implications for long term species survival in the face of environmental change. Expand