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Upregulation of miR-196a and HOTAIR drive malignant character in gastrointestinal stromal tumors.
Large intergenic noncoding RNAs (lincRNA) have been less studied than miRNAs in cancer, although both offer considerable theranostic potential. In this study, we identified frequent upregulation of… Expand
Dikkopf-1 as a novel serologic and prognostic biomarker for lung and esophageal carcinomas.
Gene expression profile analysis of lung and esophageal carcinomas revealed that Dikkopf-1 (DKK1) was highly transactivated in the great majority of lung cancers and esophageal squamous cell… Expand
Cancer-testis antigen lymphocyte antigen 6 complex locus K is a serologic biomarker and a therapeutic target for lung and esophageal carcinomas.
Gene expression profile analyses of non-small cell lung carcinomas (NSCLC) and esophageal squamous cell carcinomas (ESCC) revealed that lymphocyte antigen 6 complex locus K (LY6K) was specifically… Expand
A randomized controlled trial of endoscopic steroid injection for prophylaxis of esophageal stenoses after extensive endoscopic submucosal dissection
BackgroundEsophageal stenosis following endoscopic submucosal dissection (ESD) is a serious adverse event that makes subsequent management more difficult.MethodsThis parallel, randomized, controlled,… Expand
Characterization of an Opa interacting protein 5 involved in lung and esophageal carcinogenesis
To identify potential molecular targets for diagnosis, treatment and/or prevention of lung and esophageal carcinomas, we screened for genes that were overexpressed in tumors through gene expression… Expand
The value of narrow band imaging for early detection of laryngeal cancer
- A. Watanabe, M. Taniguchi, H. Tsujie, M. Hosokawa, M. Fujita, S. Sasaki
- European Archives of Oto-Rhino-Laryngology
- 1 July 2009
We evaluate the value of laryngoscopy using narrow band imaging (NBI) system in the diagnosis of precancerous and cancerous laryngeal lesions. Thirty-four patients were suspected of having a total of… Expand
Epigenetic inactivation of CHFR and sensitivity to microtubule inhibitors in gastric cancer.
Mitotic checkpoints prevent errors in chromosome segregation that can lead to neoplasia. Therefore, it is notable that gastric cancers often show impaired checkpoint function. In the present study,… Expand
Metachronous squamous cell carcinoma of the esophagus arising after endoscopic mucosal resection.
- Y. Shimizu, H. Tukagoshi, M. Fujita, M. Hosokawa, M. Kato, M. Asaka
- Gastrointestinal endoscopy
- 1 August 2001
BACKGROUND Endoscopic mucosal resection (EMR) is being used increasingly to treat early stage esophageal carcinoma. However, the preserved esophageal mucosa may be the source of new lesions. The aims… Expand
Adenocarcinoma arising from ectopic gastric mucosa in the cervical esophagus.
- T. Abe, M. Hosokawa, +6 authors S. Sasaki
- American journal of clinical oncology
- 1 December 2004
Ectopic (heterotopic) gastric mucosa (EGM) of the upper esophagus, referred as inlet patch, is an asymptomatic benign lesion that is often detected during endoscopic examination. Although it is… Expand
Efficacy of intense screening and treatment for synchronous second primary cancers in patients with esophageal cancer.
BACKGROUND The optimum management of esophageal cancers with synchronous second primary cancer (SPC) has not been determined. The aim of this study was to evaluate the efficacy of intense screening… Expand