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Effect of human parathyroid hormone (PTH(1-34)) on experimental osteopenia of rats induced by ovariectomy.
The effect of human PTH(1-34) on the development of osteopenia induced by ovariectomy was investigated in immature female Sprague-Dawley rats. After the surgery, human PTH(1-34) was injected… Expand
Reversible Osmotic Opening of the Blood-Brain Barrier
Reversible breakdown of the blood-brain barrier is produced by a class of electrolytes and nonelectrolytes which have little or no lipid solubility but which difler in chemical and ionic properties.… Expand
Enhancement of propranolol hydrochloride and diazepam skin absorption in vitro: effect of enhancer lipophilicity.
The enhancement of model hydrophilic (propranolol hydrochloride) and lipophilic (diazepam) drug penetration across rat and hairless mouse skin in vitro has been studied. Preliminary experiments… Expand
Polyribosomal changes during inhibition of rabbit hemoglobin synthesis by an isoleucine antagonist.
- M. Hori, M. Rabinovitz
- Chemistry, Medicine
- Proceedings of the National Academy of Sciences…
- 1 April 1968
Optimal hemoglobin synthesis in intact rabbit reticulocytes requires the presence of several amino acids in the incubation medium.1 These may be termed "essential" amino acids. The rapid hydrolysis… Expand
Artificial heart incorporated in the chest.
Theasinensin A, a tea polyphenol formed from (-)-epigallocatechin gallate, suppresses antibiotic resistance of methicillin-resistant Staphylococcus aureus.
- T. Hatano, Miwako Kusuda, M. Hori, S. Shiota, T. Tsuchiya, T. Yoshida
- Biology, Medicine
- Planta medica
- 1 November 2003
When (-)-epigallocatechin gallate (EGCG), the main constituent of tea polyphenols, was kept in a neutral buffer, it decomposed rapidly to give theasinensin A as the major product. Theasinensin A… Expand
Correlation among geometric, densitometric, and mechanical properties in mandible and femur of osteoporotic rats
- G. Jiang, H. Matsumoto, +4 authors A. Fujii
- Journal of Bone and Mineral Metabolism
- 27 February 2008
We have previously demonstrated bone loss of the mandible and femur in experimental osteoporotic rats and its prevention by medication, using peripheral quantitative computed tomography (pQCT). In… Expand
General pharmacology of the novel antiepileptic compound zonisamide. 1st communication: effects on central nervous system.
The effects of 1,2-benzisoxazole-3-methanesulfonamide (zonisamide, AD-810, CI-912), an antiepileptic compound, on the central nervous system were compared with those of carbamazepine and… Expand
Tryptophan Deficiency in Rabbit Reticulocytes: Polyribosomes during Interrupted Growth of Hemoglobin Chains
Of several amino acids essential for optimum hemoglobin synthesis by the rabbit reticulocyte, only omission of tryptophan results in polyribosome disaggregation. This disaggregation is prevented by… Expand
Benzylpiperazine derivatives. XI. Synthesis of compounds related to the metabolites of 1-[bis(4-fluorophenyl)methyl]-4-(2,3,4-trimethoxybenzyl)piperazine dihydrochloride (KB-2796).
- H. Ohtaka, M. Hori, R. Iemura, H. Yumioka
- Chemistry, Medicine
- Chemical & pharmaceutical bulletin
- 1 November 1989
The metabolites of 1-[bis(4-fluorophenyl)methyl]-4-(2,3,4-trimethoxybenzyl)piperazine dihydrochloride (KB-2796, 1), a cerebral vasodilator, and related compounds were synthesized to confirm the… Expand