Effect of Myriocin on Plasma Sphingolipid Metabolism and Atherosclerosis in apoE-deficient Mice*
Results indicate that, apart from cholesterol levels, sphingolipids have an effect on atherosclerotic development and that SPT has proatherogenic properties, and inhibition of SPT activity could be an alternative treatment for atherosclerosis.
Willingness of Iranian young adults to eat organic foods: Application of the Health Belief Model
Modulation of Presynaptic Plasticity and Learning by the H-ras/Extracellular Signal-Regulated Kinase/Synapsin I Signaling Pathway
It is demonstrated that presynaptic plasticity represents an important evolutionarily conserved mechanism for modulating learning and memory in mice and is compatible with previous invertebrate studies.
Rescue of neurological deficits in a mouse model for Angelman syndrome by reduction of αCaMKII inhibitory phosphorylation
The molecular and cellular deficits of an AS mouse model can be rescued by introducing an additional mutation at the inhibitory phosphorylation site of αCaMKII, and these double mutants no longer show the behavioral deficits seen in AS mice.
Serine palmitoyl-CoA transferase (SPT) deficiency and sphingolipid levels in mice.
Kinase activity is not required for αCaMKII-dependent presynaptic plasticity at CA3-CA1 synapses
It is demonstrated that αCaMKII has a nonenzymatic role in short-term presynaptic plasticity at hippocampal CA3-CA1 synapses and regulates the number of docked vesicles independent of its ability to be activated.
Spatial navigation impairment in mice lacking cerebellar LTD: a motor adaptation deficit?
It is shown that L7-PKCI mice are deficient in acquisition of an adapted goal-oriented behavior, part of the procedural component of the task, which supports the hypothesis that cerebellar LTD may subserve a general sensorimotor adaptation process shared by motor and spatial learning functions.
On the role of corticosterone in behavioral disorders, microbiota composition alteration and neuroimmune response in adult male mice subjected to maternal separation stress
The preparation, characterization and in vitro application evaluation of soluble soybean polysaccharide films incorporated with cinnamon essential oil nanoemulsions.
Rapid, specific, and sensitive measurements of plasma sphingomyelin and phosphatidylcholine Published, JLR Papers in Press, December 21, 2005.
Two rapid, specific, and sensitive enzymatic measurements for both phospholipids are described that are amenable to automation and can be adapted for large-scale, high-throughput assays.