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- Publications
- Influence
Multilocus Resolution of Phylogeny and Timescale in the Extant Adaptive Radiation of Hawaiian Honeycreepers
- Heather R. L. Lerner, M. Meyer, H. James, M. Hofreiter, R. Fleischer
- Biology, Medicine
- Current Biology
- 8 November 2011
Evolutionary theory has gained tremendous insight from studies of adaptive radiations. High rates of speciation, morphological divergence, and hybridization, combined with low sequence variability,… Expand
Genetic analyses from ancient DNA.
- S. Pääbo, H. Poinar, +7 authors M. Hofreiter
- Biology, Medicine
- Annual review of genetics
- 29 November 2004
About 20 years ago, DNA sequences were separately described from the quagga (a type of zebra) and an ancient Egyptian individual. What made these DNA sequences exceptional was that they were derived… Expand
DNA sequences from multiple amplifications reveal artifacts induced by cytosine deamination in ancient DNA.
- M. Hofreiter, V. Jaenicke, D. Serre, A. von Haeseler, S. Pääbo
- Biology, Medicine
- Nucleic acids research
- 1 December 2001
We show that DNA molecules amplified by PCR from DNA extracted from animal bones and teeth that vary in age between 25 000 and over 50 000 years carry C-->T and G-->A substitutions. These… Expand
Ancient DNA extraction from bones and teeth
- Nadin Rohland, M. Hofreiter
- Biology, Medicine
- Nature Protocols
- 1 July 2007
This method is designed to maximize recovery of PCR-amplifiable DNA from ancient bone and teeth specimens and at the same time to minimize co-extraction of substances that inhibit PCR. This is… Expand
Genome flux and stasis in a five millennium transect of European prehistory
- C. Gamba, E. Jones, +14 authors R. Pinhasi
- Biology, Medicine
- Nature communications
- 21 October 2014
The Great Hungarian Plain was a crossroads of cultural transformations that have shaped European prehistory. Here we analyse a 5,000-year transect of human genomes, sampled from petrous bones giving… Expand
Mitochondrial genomes reveal an explosive radiation of extinct and extant bears near the Miocene-Pliocene boundary
- J. Krause, T. Unger, +15 authors M. Hofreiter
- Medicine, Biology
- BMC Evolutionary Biology
- 28 July 2008
BackgroundDespite being one of the most studied families within the Carnivora, the phylogenetic relationships among the members of the bear family (Ursidae) have long remained unclear. Widely… Expand
Comparison and optimization of ancient DNA extraction.
- Nadin Rohland, M. Hofreiter
- Biology, Medicine
- BioTechniques
- 1 March 2007
Ancient DNA analyses rely on the extraction of the tiny amounts of DNA remaining in samples that are hundreds to tens of thousands of years old. Despite the critical role extraction efficiency plays… Expand
Assessing ancient DNA studies.
- M. Gilbert, H. Bandelt, M. Hofreiter, I. Barnes
- Biology, Medicine
- Trends in ecology & evolution
- 1 October 2005
The study of ancient DNA has the potential to make significant and unique contributions to ecology and evolution. However, the techniques used contain inherent problems, particularly with regards to… Expand
No Evidence of Neandertal mtDNA Contribution to Early Modern Humans
- D. Serre, A. Langaney, +6 authors S. Pääbo
- Biology, Medicine
- PLoS biology
- 1 March 2004
The retrieval of mitochondrial DNA (mtDNA) sequences from four Neandertal fossils from Germany, Russia, and Croatia has demonstrated that these individuals carried closely related mtDNAs that are not… Expand
Molecular coproscopy: dung and diet of the extinct ground sloth Nothrotheriops shastensis.
- H. Poinar, M. Hofreiter, +6 authors S. Pääbo
- Biology, Medicine
- Science
- 17 July 1998
DNA from excrements can be amplified by means of the polymerase chain reaction. However, this has not been possible with ancient feces. Cross-links between reducing sugars and amino groups were shown… Expand
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