• Publications
  • Influence
New substrate for determination of serum lecithin:cholesterol acyltransferase.
TLDR
Results suggest that the enzymatically measuring the decrease in unesterified cholesterol after incubation of serum with liposomes is sensitive, reproducible, and not greatly influenced by serum components.
Induction of cytochrome P450 3A (CYP 3A) by E 5110, a non-steroidal anti-inflammatory agent (NSAID), and typical CYP 3A inducers in primary cultures of dog hepatocytes.
TLDR
E 5110 was found to be nearly as effective as phenytoin, but less potent than rifampicin, on the basis of 6 beta-OH-T induction.
Specific role of an alpha,beta-unsaturated carbonyl group in gamma-glutamylcysteine synthetase induction by prostaglandin A2.
TLDR
It is suggested that an alpha,beta-unsaturated carbonyl moiety is responsible for enhancing the biosynthesis of gamma-glutamylcysteine synthetase in cultured cells.
Metabolism of isoniazid and free hydrazine formation in isolated rat hepatocytes.
TLDR
Analysis of kinetic parameters of metabolic pathways and enzymological study of rat liver homogenate revealed that hydrazine was formed preferentially from INH, catalyzed by soluble hydrolytic enzymes.
...
1
2
3
4
5
...