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The revised structure of viscosin, a peptide antibiotic.
A study of some new and useful n-terminal groups in mass spectrometry of peptides : The use of 3-hydroxyalkanoyl and unsaturated acyl groups
Abstract Using model peptides ranging from tri- to dodecapeptides, the utility of several new N-protecting groups, i.e., 3-hydroxyalkanoyl and δ 2 -acyl groups including Oct(OH), Dec(OH), Dod(OH),Expand
The structure of viscosin, a peptide antibiotic. I. Syntheses of D- and L-3-hydroxyacyl-L-leucine hydrazides related to viscosin.
All of the D- and L-3-hydroxyacyl-L-leucine hydrazides prepared showed antimicrobial activity against four kinds of microorganisms only comparable to or less than that of the saturated straight chain fatty acids of corresponding carbon numbers. Expand
Synthesis of the proposed structure of viscosin.
Two diastereoisomeric d -β-hydroxydecanoyl hexapeptides were synthesized and neither compound was not identical with viscosin, suggesting that the structure of visCosin must be reinvestigated. Expand
Syntheses and enzymic hydroxylation of protocollagen model peptides containing glutamyl or leucyl residue
The present work was carried out to examine the effect of glutamyl and leucyl residues at the X-position of -X-Pro-Glysequence on the enzymic hydroxylation of protocollagen-prolinehydroxylase. Expand
Application of mass spectrometry to sequence analysis of pyroglutamyl peptides from snake venoms: contribution to the confirmation of the amino acid sequence of bradykinin-potentiating peptides B, C
The amino acid sequences of the three bradykinin-potentiating peptides from the venom of Agkistrodon halys blomhoffii (potentiators B, C, and E) were smoothly confirmed by means of mass spectrometry coupled with enzymatic cleavage techniques. Expand
Synthesis of Viscosic Acid
The structure of viscosin, a peptide antibiotic. II. Syntheses of D- and L-3-hydroxyacylhexapeptides including the proposed structure of viscosin and its optical isomers.
Homologs of D- and L-3-hydroxyacylhexapeptide including compound (I-1c) and its optical isomers and their antibacterial properties were examined. Expand