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Masculinized Finger Length Patterns in Human Males and Females with Congenital Adrenal Hyperplasia
The ratio of the length of the second digit (2D) to the length of the fourth digit (4D) is greater in women than in men. Since androgens are involved in most somatic sex differences and since theExpand
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Sex-related variation in human behavior and the brain
  • M. Hines
  • Psychology, Medicine
  • Trends in Cognitive Sciences
  • 1 October 2010
Male and female fetuses differ in testosterone concentrations beginning as early as week 8 of gestation. This early hormone difference exerts permanent influences on brain development and behavior.Expand
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Prenatal hormones and postnatal socialization by parents as determinants of male-typical toy play in girls with congenital adrenal hyperplasia.
Toy choices of 3- to 10-year-old children with congenital adrenal hyperplasia (CAH) and of their unaffected siblings were assessed. Also assessed was parental encouragement of sex-typed toy play.Expand
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Gender development and the human brain.
  • M. Hines
  • Psychology, Medicine
  • Annual review of neuroscience
  • 21 June 2011
Convincing evidence indicates that prenatal exposure to the gonadal hormone, testosterone, influences the development of children's sex-typical toy and activity interests. In addition, growingExpand
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Fetal Testosterone Predicts Sexually Differentiated Childhood Behavior in Girls and in Boys
Mammals, including humans, show sex differences in juvenile play behavior. In rodents and nonhuman primates, these behavioral sex differences result, in part, from sex differences in androgens duringExpand
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Recommendations for the management of hemophagocytic lymphohistiocytosis in adults.
Hemophagocytic lymphohistiocytosis (HLH) is a severe hyperinflammatory syndrome induced by aberrantly activated macrophages and cytotoxic T cells. The primary (genetic) form, caused by mutationsExpand
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Comparable fMRI activity with differential behavioural performance on mental rotation and overt verbal fluency tasks in healthy men and women
To explicate the neural correlates of sex differences in visuospatial and verbal fluency tasks, we examined behavioural performance and blood-oxygenation-level-dependent (BOLD) regional brainExpand
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Developmental trajectories of sex-typed behavior in boys and girls: a longitudinal general population study of children aged 2.5-8 years.
The stability of sex-typed behavior from the preschool to the middle school years was examined. The Preschool Activities Inventory, a measure of within-sex variation in sex-typed behavior, wasExpand
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Androgens and autistic traits: A study of individuals with congenital adrenal hyperplasia
Testosterone promotes male-typical neural and behavioral development in non-human mammals. There is growing evidence that testosterone exerts similar influences on human development, although theExpand
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Androgen and psychosexual development: Core gender identity, sexual orientation, and recalled childhood gender role behavior in women and men with congenital adrenal hyperplasia (CAH)
We assessed core gender identity, sexual orientation, and recalled childhood gender role behavior in 16 women and 9 men with congenital adrenal hyperplasia (CAH) and in 15 unaffected female and 10Expand
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