Oxytocin increases trust in humans
It is shown that intranasal administration of oxytocin, a neuropeptide that plays a key role in social attachment and affiliation in non-human mammals, causes a substantial increase in trust among humans, thereby greatly increasing the benefits from social interactions.
Social support and oxytocin interact to suppress cortisol and subjective responses to psychosocial stress
Oxytocin and vasopressin in the human brain: social neuropeptides for translational medicine
- A. Meyer-Lindenberg, G. Domes, P. Kirsch, M. Heinrichs
- Psychology, BiologyNature Reviews Neuroscience
- 1 September 2011
OXT and AVP are emerging as targets for novel treatment approaches — particularly in synergistic combination with psychotherapy — for mental disorders characterized by social dysfunction, such as autism, social anxiety disorder, borderline personality disorder and schizophrenia.
Oxytocin Attenuates Amygdala Responses to Emotional Faces Regardless of Valence
Oxytocin Shapes the Neural Circuitry of Trust and Trust Adaptation in Humans
Oxytocin Improves “Mind-Reading” in Humans
Effects of intranasal oxytocin on emotional face processing in women
Predicting posttraumatic stress symptoms from pretraumatic risk factors: a 2-year prospective follow-up study in firefighters.
- M. Heinrichs, D. Wagner, W. Schoch, L. Soravia, D. Hellhammer, U. Ehlert
- Psychology, MedicineAmerican Journal of Psychiatry
- 1 December 2005
Results suggest that specific personality traits may constitute markers of vulnerability to the development of psychopathological symptoms after trauma exposure, and early identification of preexisting risk factors is needed to provide effective prevention and intervention for individuals who are at risk of developing trauma-related disorders.
Intranasal Oxytocin Increases Positive Communication and Reduces Cortisol Levels During Couple Conflict
Oxytocin Attenuates Amygdala Reactivity to Fear in Generalized Social Anxiety Disorder
It is suggested that OXT has a specific effect on fear-related amygdala activity, particularly when the amygdala is hyperactive, such as in GSAD, thereby providing a brain-based mechanism of the impact of OXT in modulating the exaggerated processing of social signals of threat in patients with pathological anxiety.