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Oxytocin increases trust in humans
TLDR
It is shown that intranasal administration of oxytocin, a neuropeptide that plays a key role in social attachment and affiliation in non-human mammals, causes a substantial increase in trust among humans, thereby greatly increasing the benefits from social interactions.
Social support and oxytocin interact to suppress cortisol and subjective responses to psychosocial stress
TLDR
Oxytocin seems to enhance the buffering effect of social support on stress responsiveness, concur with data from animal research suggesting an important role of oxytocin as an underlying biological mechanism for stress-protective effects of positive social interactions.
Oxytocin and vasopressin in the human brain: social neuropeptides for translational medicine
TLDR
OXT and AVP are emerging as targets for novel treatment approaches — particularly in synergistic combination with psychotherapy — for mental disorders characterized by social dysfunction, such as autism, social anxiety disorder, borderline personality disorder and schizophrenia.
Oxytocin Attenuates Amygdala Responses to Emotional Faces Regardless of Valence
TLDR
A modulatory role of oxytocin on amygdala responses to facial expressions irrespective of their valence is suggested, which might reflect reduced uncertainty about the predictive value of a social stimulus and thereby facilitates social approach behavior.
Oxytocin Improves “Mind-Reading” in Humans
TLDR
Oxytocin improves the ability to infer the mental state of others from social cues of the eye region, and might play a role in the pathogenesis of autism spectrum disorder, which is characterized by severe social impairment.
Oxytocin Shapes the Neural Circuitry of Trust and Trust Adaptation in Humans
TLDR
It is found that subjects in the oxytocin group show no change in their trusting behavior after they learned that their trust had been breached several times while subjects receiving placebo decrease their trust.
Effects of intranasal oxytocin on emotional face processing in women
TLDR
Group analysis revealed that the blood-oxygen-level-dependent signal was enhanced in the left amygdala, the fusiform gyrus and the superior temporal gyrus in response to fearful faces and in the inferior frontal gyrus following OXT treatment, independent of fixation pattern to specific sections of the facial stimuli.
Predicting posttraumatic stress symptoms from pretraumatic risk factors: a 2-year prospective follow-up study in firefighters.
TLDR
Results suggest that specific personality traits may constitute markers of vulnerability to the development of psychopathological symptoms after trauma exposure, and early identification of preexisting risk factors is needed to provide effective prevention and intervention for individuals who are at risk of developing trauma-related disorders.
Intranasal Oxytocin Increases Positive Communication and Reduces Cortisol Levels During Couple Conflict
TLDR
These results are in line with animal studies indicating that central oxytocin facilitates approach and pair bonding behavior, and imply an involvement of oxytocIn in couple interaction and close relationships in humans.
Oxytocin, vasopressin, and human social behavior
TLDR
This review focuses on recent knowledge of the behavioral, endocrine, genetic, and neural effects of OT and AVP in humans and provides a synthesis of recent advances made in the effort to implicate the oxytocinergic system in the treatment of psychopathological states.
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