Patellamide A and C biosynthesis by a microcin-like pathway in Prochloron didemni, the cyanobacterial symbiont of Lissoclinum patella.
- E. Schmidt, J. T. Nelson, J. Ravel
- BiologyProceedings of the National Academy of Sciences…
- 17 May 2005
The full sequencing and functional expression of a marine natural-product pathway from an obligate symbiont is presented, and a related cluster was identified in Trichodesmium erythraeum IMS101, an important bloom-forming cyanobacterium.
Variability of the mitochondrial control region in populations of the harbour porpoise, Phocoena, on interoceanic and regional scales
- P. Rosel, A. Dizon, M. Haygood
- Environmental Science
- 1 June 1995
A portion of the mitochondrial DNA control region was amplified and sequenced to characterize the amount of genetic variation within harbour porpoise populations in the Northeast Pacific, North Atlantic, and Black Sea and the utility of the control region to discriminate among putative populations along the west coast of North America was investigated.
Evidence for the Biosynthesis of Bryostatins by the Bacterial Symbiont “Candidatus Endobugula sertula” of the BryozoanBugula neritina
- S. Davidson, S. Allen, G. E. Lim, C. Anderson, M. Haygood
- BiologyApplied and Environmental Microbiology
- 1 October 2001
This study demonstrates that it may be possible to clone bryostatin genes from B. neritina directly and use these to produce brystatins in heterologous host bacteria.
Identification of sibling species of the bryozoan Bugula neritina that produce different anticancer bryostatins and harbor distinct strains of the bacterial symbiont "Candidatus Endobugula sertula".
- S. Davidson, M. Haygood
- BiologyThe Biological Bulletin
- 1 June 1999
Gene sequences from an Atlantic sample matched sequences from the California chemotype M colonies, suggesting that this type may be cosmopolitan due to transport on boat hulls, and indicates that the chemotypes represent different species.
Phylogenetic analysis of the South American electric fishes (order Gymnotiformes) and the evolution of their electrogenic system: a synthesis based on morphology, electrophysiology, and mitochondrial…
- J. Alves-Gomes, G. Ortí, M. Haygood, W. Heiligenberg, A. Meyer
- BiologyMolecular biology and evolution
- 1 March 1995
By combining molecular, morphological, and physiological information, a new hypothesis is proposed for the phylogeny of this group and a new family Eigenmanniidae n.
Phylogenetic relationships among the true porpoises (Cetacea:Phocoenidae).
- P. Rosel, M. Haygood, W. Perrin
- BiologyMolecular Phylogenetics and Evolution
- 1 December 1995
Portions of the cytochrome b gene and control region of the mitochondrial DNA molecule were sequenced to investigate systematic relationships among the six extant species of true porpoises, (Cetacea:…
Identification of the putative bryostatin polyketide synthase gene cluster from "Candidatus Endobugula sertula", the uncultivated microbial symbiont of the marine bryozoan Bugula neritina.
- S. Sudek, N. Lopanik, M. Haygood
- BiologyJournal of Natural Products
- 2007
As "E. sertula" is to date uncultured, heterologous expression of this biosynthetic gene cluster has the potential of producing the bioactive bryostatins in large enough quantities for development into a pharmaceutical.
Identification of the antifungal peptide-containing symbiont of the marine sponge Theonella swinhoei as a novel δ-proteobacterium, “Candidatus Entotheonella palauensis”
- E. Schmidt, A. Obraztsova, S. Davidson, D. Faulkner, M. Haygood
- Biology
- 2000
The 16S rRNA gene sequence was determined using a combination of denaturing gradient-gel electrophoresis (DGGE) and specific polymerase chain-reaction (PCR) primers, and its source was confirmed by in situ hybridization.
Self-assembling amphiphilic siderophores from marine bacteria.
- J. S. Martinez, G. P. Zhang, A. Butler
- BiologyScience
- 18 February 2000
Two families of siderophores were isolated from strains belonging to two different genera of marine bacteria, suggesting that unique iron acquisition mechanisms may have evolved in marine bacteria.
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