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Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs
Empirical evidence of shared genetic etiology for psychiatric disorders can inform nosology and encourages the investigation of common pathophysiologies for related disorders. Expand
[Sex differences in depression].
- M. Hautzinger
- Zeitschrift fur klinische Psychologie…
Most etiologic theories for depression do not take into account sex differences in depression, and the need for more empirical and longitudinal research is obvious. Expand
Genome-wide association study identifies 30 Loci Associated with Bipolar Disorder
The largest genome-wide association study to date, including 20,352 cases and 31,358 controls of European descent, with follow-up analysis of 881 sentinel variants at loci with P<1×10-4, achieves genome- wide significance including 18 novel loci, which provide potential new biological mechanisms for bipolar disorder. Expand
[The Beck Depression Inventory in clinical practice].
- M. Hautzinger
- Psychology, Medicine
- Der Nervenarzt
- 1 November 1991
The German version of the Beck Depression Inventory was administered to 477 depressed in- and out-patients, 180 patients with chronic pain and 86 matched healthy control subjects and proved to be a useful psychometric instrument for measuring the intensity of depressive symptoms in clinical samples. Expand
Genome-wide association study reveals two new risk loci for bipolar disorder.
Results from the largest BD GWAS to date are presented by investigating 2.3 million single-nucleotide polymorphisms (SNPs) in a sample of 24,025 patients and controls and detecting 56 genome-wide significant SNPs in five chromosomal regions including previously reported risk loci ANK3, ODZ4 and TRANK1. Expand
[Reliability and validity of the Revised Beck Depression Inventory (BDI-II). Results from German samples].
The German BDI-II demonstrates good reliability and validity in clinical and nonclinical samples and may now replace the older version of the BDI for assessing self-rated severity of depression and course of depressed symptoms under treatment. Expand
Genotype–phenotype relationship in female carriers of the premutation and full mutation of FMR-1
It is suggested that social avoidance (expressed as social phobia or avoidant personality disorder) has been underestimated in previous studies of carriers with the FMR-1 full mutation or premutation. Expand
I can see what you feel, but I can't deal with it: Impaired theory of mind in depression.
- L. Wolkenstein, M. Schönenberg, Evelyne Schirm, M. Hautzinger
- Medicine, Psychology
- Journal of affective disorders
- 1 July 2011
It is possible that the low level of social functioning associated with depression can be ascribed partially to a ToM deficit and should be addressed in the treatment of depression. Expand
Impulsivity in Binge Eating Disorder: Food Cues Elicit Increased Reward Responses and Disinhibition
Food-related reward sensitivity and rash-spontaneous behaviour, as the two components of impulsivity, are increased in BED in comparison with weight-matched and normal-weight controls, indicating that BED represents a neurobehavioural phenotype of obesity that is characterised by increased impulsivity. Expand