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Prolactin proteolysis by glandular kallikrein: in vitro reaction requirements and cleavage sites, and detection of processed prolactin in vivo.
Glandular kallikrein (GK) is a trypsin-like serine protease characterized by an ability to generate bioactive peptides from inactive precursors with high specificity. In rat pituitary lactotrophs, GK… Expand
Differential responses of pituitary kallikrein and prolactin to tamoxifen and chlorotrianisene
- C. A. Powers, M. Hatala, P. J. Pagano
- Biology, Medicine
- Molecular and Cellular Endocrinology
- 1 September 1989
Glandular kallikrein, a trypsin-like serine protease, and prolactin (PRL) are both estrogen-induced proteins in rat anterior pituitary lactotrophs. The estrogen agonist and antagonist effects of… Expand
Temporomandibular joint axiography and MRI findings: a comparative study.
- K. Parlett, D. Paesani, R. Tallents, M. Hatala
- The Journal of prosthetic dentistry
- 1 December 1993
Axiography may be useful in the evaluation of condyle motion and the effects of internal derangements on this motion. Fifty-one patients were selected by one investigator (RHT) to provide a… Expand
Angle of the articular eminence in patients with temporomandibular joint dysfunction and asymptomatic volunteers.
- G. Galante, D. Paesani, R. Tallents, M. Hatala, R. Katzberg, W. Murphy
- Oral surgery, oral medicine, oral pathology, oral…
- 1 August 1995
OBJECTIVE The purpose of this study was to compare structural variations of the temporomandibular joint anatomy between symptomatic patients with temporomandibular joint dysfunction and asymptomatic… Expand
Effects of dietary fish oil on fatty acids and eicosanoids in metastasizing human breast cancer cells.
We examined the relationships between the suppressive effects of dietary fish oil on growth and metastasis of MDA-MB-435 human breast cancer cells in female nude mice and the primary tumor… Expand
Effects of phenobarbital and 3-methylcholanthrene induction on the formation of three glucuronide metabolites of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, NNK.
- S. Murphy, Márcia Gaspar Nunes, M. Hatala
- Chemistry, Medicine
- Chemico-biological interactions
- 14 March 1997
4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) is a tobacco specific carcinogen believed to be a causative agent for human lung cancer. To exert its carcinogenic potential, NNK must be… Expand
Myocardial Salvage Induced by REV‐5901: An Inhibitor and Antagonist of the Leukotrienes
- K. Mullane, M. Hatala, R. Kraemer, W. Sessa, W. Westlin
- Journal of cardiovascular pharmacology
- 1 October 1987
Summary: Lipoxygenase metabolites of arachidonic acid have been implicated in myocardial injury induced by coronary artery occlusion and reperfusion, as dual inhibitors of the lipoxygenase and… Expand
Effect of diets containing different levels of linoleic acid on human breast cancer growth and lung metastasis in nude mice.
The purpose of the study was to determine the effect of three different levels of dietary linoleic acid (LA) intake on the growth of MDA-MB-435 human breast cancer cells in the mammary fat pads of… Expand
Comparison of linoleic acid and eicosapentaenoic acid incorporation into human breast cancer cells
To gain some insight into the mechanisms involved in the opposing effects of linoleic acid (LA) and eicosapentaenoic acid (EPA) on the growth and invasiveness of MDA-MB-435 human breast cancer cells,… Expand
Dietary fatty acids and breast cancer invasion and metastasis.
This review presents the evidence for the hypothesis that dietary linoleic acid and its metabolic derivative arachidonic acid enhance the metastatic process in breast cancer. Key biochemical events… Expand