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Intestinal bacterial metabolism of flavonoids and its relation to some biological activities
Flavonoid glycosides were metabolized to phenolic acids via aglycones by human intestinal microflora producing α-rhamnosidase, exo-β-glucosidase, endo-β-glucosidase and/or β-glucuronidase. Rutin,Expand
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Ginsenoside Rh1 Possesses Antiallergic and Anti-Inflammatory Activities
Background: Ginseng (the root of Panax ginseng C.A. Meyer, Araliaceae) has been reported to possess various biological activities, including anti-inflammatory and antitumor actions. In this study, weExpand
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Transformation of ginseng saponins to ginsenoside rh2 by acids and human intestinal bacteria and biological activities of their transformants
When ginseng water extract was incubated at 60°C in acidic conditions, its protopanaxadiol ginsenosides were transformed to ginsenoside Rg3 and ▵20-ginsenoside Rg3. However, protopanaxadiol glycosideExpand
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Metabolism of 20(S)- and 20(R)-ginsenoside Rg3 by human intestinal bacteria and its relation to in vitro biological activities.
When ginsenoside Rg3 was anaerobically incubated with human fecal microflora, all specimens metabolized ginsenoside Rg3 to ginsenoside Rh2 and protopanaxadiol. The main metabolite was ginsenosideExpand
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Hepatoprotective effect of ginsenoside Rb1 and compound K on tert‐butyl hydroperoxide‐induced liver injury
Abstract: Background/Aim: The main component of Panax ginseng, which have been reported by many researchers, are ginsenoside Rb1, Rb2 and Rc. Orally administered ginsenosides are metabolized toExpand
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Lactobacillus pentosus var. plantarum C29 ameliorates memory impairment and inflammaging in a D-galactose-induced accelerated aging mouse model.
Aging is associated with Alzheimer's disease (AD), cardiovascular disease and cancer. Oxidative stress is considered as a major factor that accelerates the aging process. To understand the ability ofExpand
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Effects of reactive oxygen species on proliferation of Chinese hamster lung fibroblast (V79) cells.
Reactive oxygen species (ROS) have emerged as important signaling molecules in the regulation of various cellular processes. In our study, we investigated the effect of a wide range of ROS on ChineseExpand
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Anti-Helicobacter pylori activity of the metabolites of poncirin from Poncirus trifoliata by human intestinal bacteria.
Poncirin was isolated from water extract of the fruits of Poncirus trifoliata and metabolized by human intestinal bacteria. The inhibitory effect of poncirin and its metabolites by these bacteria onExpand
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Anti-Helicobacter pylori activity of herbal medicines.
The extracts of Coptidis japonica (rhizoma), Eugenia caryophyllata (flower), Rheum palmatum (rhizoma), Magnolia officinalis (cortex) and Rhusjavanica (galla rhois) potently inhibited the growth ofExpand
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Metabolism of puerarin and daidzin by human intestinal bacteria and their relation to in vitro cytotoxicity.
When puerarin or daidzin were incubated for 24 h with human intestinal bacteria, two metabolites, daidzein and calycosin, were produced from them, respectively. The metabolic time course of puerarinExpand
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