A High-Coverage Genome Sequence from an Archaic Denisovan Individual
The genomic sequence provides evidence for very low rates of heterozygosity in the Denisova, probably not because of recent inbreeding, but instead because of a small population size, and illuminates the relationships between humans and archaics, including Neandertals, and establishes a catalog of genetic changes within the human lineage.
The Simons Genome Diversity Project: 300 genomes from 142 diverse populations
It is demonstrated that indigenous Australians, New Guineans and Andamanese do not derive substantial ancestry from an early dispersal of modern humans; instead, their modern human ancestry is consistent with coming from the same source as that of other non-Africans.
New binary polymorphisms reshape and increase resolution of the human Y chromosomal haplogroup tree.
- T. Karafet, F. Mendez, Monica B. Meilerman, P. Underhill, S. Zegura, M. Hammer
- BiologyGenome Research
- 1 May 2008
Major changes in the topology of the parsimony tree are described and names for new and rearranged lineages within the tree following the rules presented by the Y Chromosome Consortium in 2002 are provided.
Ancient human genomes suggest three ancestral populations for present-day Europeans
It is shown that most present-day Europeans derive from at least three highly differentiated populations: west European hunter-gatherers, who contributed ancestry to all Europeans but not to Near Easterners; ancient north Eurasians related to Upper Palaeolithic Siberians; and early European farmers, who were mainly of Near Eastern origin but also harboured west Europeanhunter-gatherer related ancestry.
Great ape genetic diversity and population history
This comprehensive catalogue of great ape genome diversity provides a framework for understanding evolution and a resource for more effective management of wild and captive great ape populations.
Out of Africa and back again: nested cladistic analysis of human Y chromosome variation.
It is inferred that one of the oldest events in the nested cladistic analysis was a range expansion out of Africa which resulted in the complete replacement of Y chromosomes throughout the Old World, a finding consistent with many versions of the Out of Africa Replacement Model.
Dual origins of the Japanese: common ground for hunter-gatherer and farmer Y chromosomes
Coalescent analyses of Y chromosome short tandem repeat diversity indicated that haplogroups D and C began their expansions in Japan ∼20,000 and ∼12,000 years ago, respectively, while haplogroup O-47z began its expansion only ∼4,400 years ago.
Paternal population history of East Asia: sources, patterns, and microevolutionary processes.
The peopling of East Asia was more complex than earlier models had proposed-that is, a multilayered, multidirectional, and multidisciplinary framework is necessary.
A recent insertion of an alu element on the Y chromosome is a useful marker for human population studies.
- M. Hammer
- BiologyMolecular biology and evolution
- 1 September 1994
Phylogenetic comparisons with other Alu sequences reveal that the YAP element is a member of the polymorphic subfamily-3 (PSF-3), a previously undefined subfamily of Alu elements, which support the hypothesis that recently inserted elements result from multiple source genes.
A recent common ancestry for human Y chromosomes
- M. Hammer
- 23 November 1995
Inferences contradict predictions of the multiregional hypothesis positing a widespread transformation of Homo erectus populations into Homo sapiens and are consistent with auto-somal and mitochondrial DNA studies that suggest a long-term human effective population size of 10,000 and a sex ratio of 1.