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From olive drupes to olive oil. An HPLC-orbitrap-based qualitative and quantitative exploration of olive key metabolites.
The current study discloses the chemical nature of different olive materials in a successive and integrated way and reveals new sources of high added value constituents of olives. Expand
The Antioxidant Effects of a Polyphenol-Rich Grape Pomace Extract In Vitro Do Not Correspond In Vivo Using Exercise as an Oxidant Stimulus
The findings indicate that the tested grape pomace extract exhibits potent in vitro antioxidant properties because it scavenges the DPPH• and ABTS•+ radicals and inhibits DNA damage induced by peroxyl and hydroxyl radicals. Expand
Walnut extract (Juglans regia L.) and its component ellagic acid exhibit anti-inflammatory activity in human aorta endothelial cells and osteoblastic activity in the cell line KS483
The present results suggest that the walnut extract has a high anti-atherogenic potential and a remarkable osteoblastic activity, an effect mediated, at least in part, by its major component ellagic acid, which implicate the beneficial effect of a walnut-enriched diet on cardioprotection and bone loss. Expand
UHPLC-DAD-FLD and UHPLC-HRMS/MS based metabolic profiling and characterization of different Olea europaea organs of Koroneiki and Chetoui varieties §
It is noticeable that except olive oil, diverse organs of olive tree might comprise an alternative and valuable source of biologically active compounds. Expand
Pyrrolizidine alkaloids in medicinal tea of Ageratum conyzoides
To date, there are no established safety guidelines on pyrrolizidine alkaloids-containing plants, and their use in Brazil, and thirteen phenolic compounds were identified, notably, methoxylated flavonoids and chromenes. Expand
Characteristics, Phytochemical Analysis and Biological Activities of Extracts from Tunisian Chetoui Olea europaea Variety
This study selected 10 extracts from Tunisian chetoui O. europaea variety for their total phenolics, flavonoids, and phytochemical analyses as well as for their antioxidant and antimicrobialExpand
Recent advances and new strategies in the NMR-based identification of natural products.
The introduction and utilization of technical improvements such as miniaturized and crycogenic NMR probes along with hyphenation capabilities and computational support could lead NPs research to more comprehensive structure identification and new holistic perspectives. Expand
Estrogenic activity of isoflavonoids from Onobrychis ebenoides.
The data suggest that the C-8 isoprenyl substituent of 1 renders it cytotoxic and/or estrogenic in a cell-dependent manner. Expand
Structure-oriented UHPLC-LTQ Orbitrap-based approach as a dereplication strategy for the identification of isoflavonoids from Amphimas pterocarpoides crude extract.
A new structure-oriented approach based on fast UHPLC-high-resolution (HR)MS and HRMS/MS methodologies for the identification of isoflavonoids in crude extracts is developed to assist dereplication procedures, to decrease the laborious isolation steps and orient the focused isolation of compounds of interest. Expand
One-step semisynthesis of oleacein and the determination as a 5-lipoxygenase inhibitor.
By exploiting oleuropein isolated from the plant leaf extract, an efficient procedure has been developed for a one-step semisynthesis of oleacein under Krapcho decarbomethoxylation conditions, facilitating the further development as a potential anti-inflammatory agent. Expand