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Effects of nonylphenol, bisphenol A, and their mixture on the viviparous swordtail fish (Xiphophorus helleri).
- H. I. Kwak, M. Bae, +10 authors M. H. Cho
- Biology, Medicine
- Environmental toxicology and chemistry
- 1 April 2001
A number of fish species have been used for studies on endocrine disrupting chemicals (EDCs). However, despite the widespread use of oviparous fish, relatively little attention has been given to… Expand
Exposure to 4-tert-octylphenol, an environmentally persistent alkylphenol, enhances interleukin-4 production in T cells via NF-AT activation.
4-tert-Octylphenol (OP) is a representative endocrine disruptor that may have adverse effects on human health. The influence of this compound on allergic immune responses remains unclear. In this… Expand
Enhancement of Interleukin-4 Production in Activated CD4+ T Cells by Diphthalate Plasticizers via Increased NF-AT Binding Activity
- M. H. Lee, Jin Park, S. W. Chung, B. Y. Kang, S. Kim, T. Kim
- Medicine, Biology
- International Archives of Allergy and Immunology
- 1 June 2004
Background: Diethylhexyl phthalate (DEHP) and diisononyl phthalate (DINP), two commonly used plasticizers in flexible polyvinylchloride formulations, have potentially adverse effects on human health.… Expand
Immunotoxicity of ethyl carbamate in female BALB/c mice: role of esterase and cytochrome P450.
- S. Cha, H. K. Gu, K. P. Lee, M. H. Lee, S. Han, T. Jeong
- Chemistry, Medicine
- Toxicology letters
- 5 June 2000
Ethyl carbamate, a potent carcinogen, has been characterized to be metabolized by cytochrome P450 (P450) and esterase. It has recently been demonstrated that P450 may activate ethyl carbamate to… Expand
Dose-independent pharmacokinetics of a new neuroprotective agent for ischemia-reperfusion damage, KR-31543, after intravenous and oral administration to rats: hepatic and intestinal first-pass…
The purpose of this study was to report dose-independent pharmacokinetics of KR-31543, a new neuroprotective agent for ischemia-reperfusion damage, after intravenous (iv) and oral (po) administration… Expand
Role of corticosterone in ethyl carbamate-induced immunosuppression in female BALB/c mice.
We have recently demonstrated that the antibody response to the T-cell-dependent antigen, sheep red blood cells (SRBCs), was suppressed by ethyl carbamate in female BALB/c mice. At the same doses,… Expand
Leukemic glaucoma in a patient with chronic myeloid leukemia treated by intracameral methotrexate
Induction of pro-inflammatory cytokines by 29-kDa FN-f via cGAS/STING pathway
The cGAS-STING pathway plays an important role in pathogen-induced activation of the innate immune response. The 29-kDa amino-terminal fibronectin fragment (29-kDa FN-f) found predominantly in the… Expand
Oviductural carcinoma in B6C3F1 female mice exosed to 0.5 ppm ozone.
- M. Kim, J. Son, M. H. Cho, C. S. Choi, C. H. Chae, M. H. Lee
- Veterinary and human toxicology
- 1 December 2001
The toxicity and carcinogenecity of ozone was evaluated in B6C3F1 mice exposed to 0.5 ppm ozone via inhalation for 12 w, during which no ozone-related deaths occurred. Decreases in mean body weights… Expand
NOD2 signaling pathway is involved in fibronectin fragment-induced pro-catabolic factor expressions in human articular chondrocytes
The nucleotide-binding and oligomerization domain (NOD) is an innate pattern recognition receptor that recognizes pathogen- and damage-associated molecular patterns. The 29-kDa amino-terminal… Expand