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In vitro discovery of promising anti-cancer drug combinations using iterative maximisation of a therapeutic index
In vitro-based search for promising anti-cancer drug combinations may provide important leads to improved cancer therapies. Currently there are no integrated computational-experimental methods… Expand
392 A SELECTIVE ESTROGEN RECEPTOR BETA AGONIST MODULATES NEUROPATHIC AND INFLAMMATORY PAIN STATES
Background and aims. The effects of estrogens on pain perception remain quite controversial. Depending on the animal models, both beneficial and detrimental effects of non-selective estrogens have… Expand