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Seasonal variations in chemical composition and in vitro biological effects of fine PM from Milan.
Fine particulate matter (PM1 and PM2.5) was collected in Milan over the summer (August-September) and winter (January-March) seasons of 2007/2008. Particles were analyzed for their chemicalExpand
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Differences in cytotoxicity versus pro-inflammatory potency of different PM fractions in human epithelial lung cells.
Air pollution in Milan causes health concern due to the high concentrations of particulate matter (PM10 and PM2.5). The aim of this study was to investigate possible seasonal differences in PM10 andExpand
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Toxicity of tire debris leachates.
Data on the indicators of environmental impact of tire debris, originated from the tire abrasion on roads, are extremely scarce, while it is well known that tires may produce deleterious effects.Expand
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Comparison of non-crystalline silica nanoparticles in IL-1β release from macrophages
BackgroundRespirable crystalline silica (silicon dioxide; SiO2, quartz) particles are known to induce chronic inflammation and lung disease upon long-term inhalation, whereas non-crystallineExpand
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First evidence of tyre debris characterization at the nanoscale by focused ion beam
In this paper, we present a novel technique for the nanoscale characterization of the outer and inner structure of tyre debris. Tyre debris is produced by the normal wear of tyres. In previousExpand
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Winter fine particulate matter from Milan induces morphological and functional alterations in human pulmonary epithelial cells (A549).
Samples of PM(2.5) were gravimetrically collected during the winter 2005/2006 in the urban area of Milan (North Italy). Samples were chemically characterized and the particles were detached fromExpand
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Particle size, chemical composition, seasons of the year and urban, rural or remote site origins as determinants of biological effects of particulate matter on pulmonary cells.
Particulate matter (PM), a complex mix of chemical compounds, results to be associated with various health effects. However there is still lack of information on the impact of its differentExpand
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Nickel oxide nanoparticles induce inflammation and genotoxic effect in lung epithelial cells.
Nickel oxide nanoparticles (NiONPs) toxicity has been evaluated in the human pulmonary epithelial cell lines: BEAS-2B and A549. The nanoparticles, used at the doses of 20, 40, 60, 80, 100 μg/ml,Expand
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Impact of tire debris on in vitro and in vivo systems
BackgroundIt is estimated that over 80% of respirable particulate matter (PM10) in cities comes from road transport and that tire and brake wear are responsible for the 3–7% emission of it. Data onExpand
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The modality of cell-particle interactions drives the toxicity of nanosized CuO and TiO₂ in human alveolar epithelial cells.
Metal oxide NPs are abundantly produced in nanotech industries and are emitted in several combustion processes, suggesting the need to characterize their toxic impact on the human respiratory system.Expand
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