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MiR-204-5p suppresses cell proliferation by inhibiting IGFBP5 in papillary thyroid carcinoma.
Apigenin Protects Against Renal Tubular Epithelial Cell Injury and Oxidative Stress by High Glucose via Regulation of NF-E2-Related Factor 2 (Nrf2) Pathway
TLDR
Apigenin protects renal tubular epithelial cells against high glucose-induced injury through suppression of oxidative stress and inflammation via activation of the Nrf2 pathway.
Emerging roles for PIWI proteins in cancer.
TLDR
PIWI proteins are linked to the hallmarks of cancer defined by Weinberg and Hanahan, such as cell proliferation, anti-apoptosis, genomic instability, invasion and metastasis, which provides new possibilities for anticancer therapies through the targeting of PIWI proteins.
Effects of Aldosterone on Chemerin Expression And Secretion in 3T3-L1 Adipocytes.
  • Junhua Ma, Fei Sun, M. Gu
  • Biology, Medicine
    Experimental and clinical endocrinology…
  • 20 September 2017
TLDR
The data demonstrate a direct interaction between aldosterone and chemerin in adipocytes, which may be an underlying mechanism linking ald testosterone-associated metabolic abnormalities and cardiovascular disease.
Gene expression changes in human mesenchymal stem cells from patients with osteoporosis
TLDR
The DEGs with high degree in the PPI and transcriptional regulatory networks may be candidate target molecules, which may be used to monitor, diagnose and treat osteoporosis.
Reduced colorectal cancer incidence in type 2 diabetic patients treated with metformin: a meta-analysis
TLDR
The meta-analysis suggests metformin may reduce CRC incidence among diabetics, which is useful medical information for clinicians.
Association of subclinical thyroid dysfunction with bone mineral density and fracture: a meta-analysis of prospective cohort studies
TLDR
Subclinical hyperthyroidism could induce additional risk on fractures at any, hip, spine, and non-spine, whereas subclinical hypothyroidism did not have any impact on fractures.
Existing bitter medicines for fighting 2019‐nCoV‐associated infectious diseases
TLDR
It is suggested that a cocktail‐like recipe of existing bitter drugs may help doctors to fight this catastrophic disease and that the general public may drink or eat bitter substances, such as coffee, tea, or bitter vegetables, to reduce the risk of infection.
Quantitative Assessment of Common Genetic Variants on FOXE1 and Differentiated Thyroid Cancer Risk
TLDR
It is demonstrated that common variations of FOXE1 are a risk factor associated with increased TC susceptibility and heterogeneity largely disappeared after stratification by ethnicity.
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