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Convergent Findings of Altered Functional and Structural Brain Connectivity in Individuals with High Functioning Autism: A Multimodal MRI Study
Brain tissue changes in autism spectrum disorders seem to be rather subtle and widespread than anatomically distinct. Therefore a multimodal, whole brain imaging technique appears to be anExpand
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In vivo staging of regional amyloid deposition
Objectives: To estimate a regional progression pattern of amyloid deposition from cross-sectional amyloid-sensitive PET data and evaluate its potential for in vivo staging of an individual's amyloidExpand
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Brain volumes differ between diagnostic groups of violent criminal offenders
Studies on structural abnormalities in antisocial individuals have reported inconsistent results, possibly due to inhomogeneous samples, calling for an investigation of brain alterations inExpand
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Multimodal analysis of functional and structural disconnection in Alzheimer's disease using multiple kernel SVM
Alzheimer's disease (AD) patients exhibit alterations in the functional connectivity between spatially segregated brain regions which may be related to both local gray matter (GM) atrophy as well asExpand
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Atrophy of the cholinergic basal forebrain in dementia with Lewy bodies and Alzheimer’s disease dementia
Similar to Alzheimer’s disease (AD), dementia with Lewy bodies (DLB) is characterized by a profound degeneration of cortically-projecting cholinergic neurons of the basal forebrain (BF) andExpand
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Multimodal imaging in Alzheimer's disease: validity and usefulness for early detection
Alzheimer's disease is a progressive neurodegenerative disease that typically manifests clinically as an isolated amnestic deficit that progresses to a characteristic dementia syndrome. Advances inExpand
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Subregional basal forebrain atrophy in Alzheimer's disease: a multicenter study.
Histopathological studies in Alzheimer's disease (AD) suggest severe and region-specific neurodegeneration of the basal forebrain cholinergic system (BFCS). Here, we studied the between-centerExpand
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In vivo cholinergic basal forebrain atrophy predicts cognitive decline in de novo Parkinson’s disease
See Gratwicke and Foltynie (doi:10.1093/brain/awx333) for a scientific commentary on this article. Cognitive impairments in Parkinson’s disease show variable onset, severity and progression. Ray etExpand
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Relevance of magnetic resonance imaging for early detection and diagnosis of Alzheimer disease.
Hippocampus volumetry currently is the best-established imaging biomarker for AD. However, the effect of multicenter acquisition on measurements of hippocampus volume needs to be explicitlyExpand
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Longitudinal measures of cholinergic forebrain atrophy in the transition from healthy aging to Alzheimer's disease
Recent evidence from cross-sectional in vivo imaging studies suggests that atrophy of the cholinergic basal forebrain (BF) in Alzheimer's disease (AD) can be distinguished from normal age-relatedExpand
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