• Publications
  • Influence
Cardiac involvement in patients with sarcoidosis: diagnostic and prognostic value of outpatient testing.
TLDR
A structured clinical assessment incorporating advanced cardiac imaging with PET scanning or CMRI is more sensitive than the established criteria for the identification of CS in ambulatory patients with preserved cardiac function, who appear to be at low risk for short-term mortality. Expand
Feasibility and potential clinical utility of goal-directed transthoracic echocardiography performed by noncardiologist intensivists using a small hand-carried device (SonoHeart) in critically ill
TLDR
Surgical intensivists successfully performed and correctly interpreted a limited transthoracic echocardiographic system in intensive care unit patients, and this study supports incorporating bedside goal-directed, limited TTE into intensivist' training programs. Expand
Prevalence of metabolic syndrome in retired National Football League players.
TLDR
Findings may partially explain the increased risk for cardiovascular death observed in retired linemen and could have significant public health implications for preprofessional training regimens and postprofessional health maintenance. Expand
Adjusted-dose warfarin versus low-intensity, fixed-dose warfarin plus aspirin for high-risk patients with atrial fibrillation: Stroke Prevention in Atrial Fibrillation III randomised clinical trial
TLDR
Low-intensity, fixed-dose warfarin plus aspirin in this regimen is insufficient for stroke prevention in patients with non-valvular AF at high-risk for thromboembolism; adjusted-doseWarfarin (target INR 2.0-3.0) importantly reduces stroke for high- risk patients. Expand
Pathophysiologic correlates of thromboembolism in nonvalvular atrial fibrillation: I. Reduced flow velocity in the left atrial appendage (The Stroke Prevention in Atrial Fibrillation [SPAF-III]
TLDR
The role of reduced LAA Anu(p) is reduced in AF and associated with spontaneous echocardiographic contrast, appendage thrombus, and cardioembolic stroke, although other mechanisms also contribute to stroke. Expand
In vivo magnetic resonance evaluation of atherosclerotic plaques in the human thoracic aorta: a comparison with transesophageal echocardiography.
TLDR
This study demonstrates that noninvasive MR evaluation of the aorta compares well with TEE imaging for the assessment of atherosclerotic plaque thickness, extent, and composition. Expand
Pulmonary hypertension in type 1 Gaucher's disease: genetic and epigenetic determinants of phenotype and response to therapy.
TLDR
Progression to severe, life-threatening PH occurs in the presence of additional genetic factors (non-N370S GBA mutation, positive family history, and ACE I gene polymorphism) and epigenetic modifiers (i.e., asplenia and female sex) and ERT+/-vasodilators/coumadin should be initiated. Expand
Incidence of subclinical atherosclerosis as a marker of cardiovascular risk in retired professional football players.
TLDR
Despite their elite athletic histories, former professional football players have a similar prevalence of advanced subclinical atherosclerosis as a clinically referred population of overweight and obese men. Expand
Echocardiographic "smoke" is produced by an interaction of erythrocytes and plasma proteins modulated by shear forces.
TLDR
Echogenic smoke appears to be due primarily to the interaction of red blood cells and plasma proteins at low flow and low shear rate conditions. Expand
...
1
2
3
4
5
...