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Dual role of arginine metabolism in establishing pathogenesis.
Arginine is an integral part of host defense when invading pathogens are encountered. The arginine metabolite nitric oxide (NO) confers antimicrobial properties, whereas the metabolite ornithine isExpand
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Salmonella escapes adaptive immune response via SIRT2 mediated modulation of innate immune response in dendritic cells
Salmonella being a successful pathogen, employs a plethora of immune evasion mechanisms. This contributes to pathogenesis, persistence and also limits the efficacy of available treatment. All theseExpand
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Human–Wildlife Interactions: Turning Conflict into Coexistence edited by Beatrice Frank, Jenny A. Glikman & Silvio Marchini (2019) 476 pp., Cambridge University Press, Cambridge, UK. ISBN
Fifteen years ago when Cambridge University Press published People and Wildlife: Conflict or Coexistence? it was one of the first books to bring the term ‘coexistence’ into conservation parlance,Expand
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Lactoylglutathione lyase, a critical enzyme in methylglyoxal detoxification, contributes to survival of Salmonella in the nutrient rich environment
Glyoxalase I which is synonymously known as lactoylglutathione lyase is a critical enzyme in methylglyoxal (MG) detoxification. We assessed the STM3117 encoded lactoylglutathione lyase (Lgl) ofExpand
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Salmonella escapes antigen presentation through K63 ubiquitination mediated endosomal proteolysis of MHC II via modulation of endosomal acidification in dendritic cells
CD4+ T-cell response is vital for successful clearance of Salmonella Typhimurium infection. Efficient antigen presentation is crucial for effective CD4+ T-cell response. Previous study has reportedExpand
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Hoodwinking the Big-Eater to Prosper: The Salmonella-Macrophage Paradigm
Salmonella is a major cause of morbidity and mortality in the developing and underdeveloped nations. Being a foodborne disease, Salmonella infection is primarily contracted through the ingestion ofExpand
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Emotional coping among communities affected by wildlife–caused damage in north-east India: opportunities for building tolerance and improving conservation outcomes
Abstract Human–wildlife conflict has been the focus of much research, and incidents of damage caused by wildlife to communities, as well as damage inflicted on wildlife by people, have been studiedExpand
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Group-2 innate lymphoid cell-dependent regulation of tissue neutrophil migration by alternatively activated macrophage-secreted Ear11
Type-2 immunity is characterised by interleukin (IL)-4, IL-5 and IL-13, eosinophilia, mucus production, IgE, and alternatively activated macrophages (AAM). However, despite the lack of neutrophilExpand
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BET Bromodomain Inhibitor iBET151 Impedes Human ILC2 Activation and Prevents Experimental Allergic Lung Inflammation
Group 2 innate lymphoid cells (ILC2) increase in frequency in eczema and allergic asthma patients, and thus represent a new therapeutic target cell for type-2 immune-mediated disease. The bromodomainExpand
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Biofilm formation by bacterial isolates from patients on indwelling medical devices
72% of biofilm producing enterobacteriaceae isolates were MDR whereas only 57.1% non-biofilm producers were MDR. Fifty percent of biofilm producing S.aureus isolates were MRSA whereas only 33%Expand
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