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Health disadvantage in US adults aged 50 to 74 years: a comparison of the health of rich and poor Americans with that of Europeans.
The poorest Americans experience the greatest disadvantage relative to Europeans, but differences were more marked among the poor than in the United States and England.
Contribution of vascular risk factors to the progression in Alzheimer disease.
Higher prediagnosis total cholesterol and LDL-C concentrations and history of diabetes were associated with faster cognitive decline in patients with incident AD, which provides further evidence for the role of vascular risk factors in the course of AD.
Lifecourse Social Conditions and Racial and Ethnic Patterns of Cognitive Aging
Contextual factors that shape the environmental conditions encountered by racial and ethnic minorities in the United States, in particular African-Americans are discussed, including cognitive aging.
Inequalities in dementia incidence between six racial and ethnic groups over 14 years
Reducing racial/ethnic disparities is a primary objective of the National Alzheimer's Plan (NAPA), yet direct comparisons within large samples representing diversity of the United States are lacking.
Does cognitive reserve shape cognitive decline?
The objective is to examine the impact of 3 markers of reserve from different points in the life course on cognitive function and decline in late adulthood.
Instrumental variable estimation in a survival context.
This article develops the IV approach for regression analysis in a survival context, primarily under an additive hazards model, for which it is established that analogous strategies can also be used under a proportional hazards model specification, provided the outcome is rare over the entire follow-up.
Epidemiologists typically seek to answer causal questions using statistical data: we observe a statistical association between poverty and early mortality and seek to determine whether poverty causes
Older age at retirement is associated with decreased risk of dementia
The results indicate the potential importance of maintaining high levels of cognitive and social stimulation throughout work and retiree life and show strong evidence of a significant decrease in the risk of developing dementia associated with older age at retirement, in line with the "use it or lose it" hypothesis.
Addressing Social Determinants of Health and Health Disparities: A Vital Direction for Health and Health Care
This publication is part of the National Academy of Medicine’s Vital Directions for Health and Health Care Initiative, which called on more than 150 leading researchers, scientists, and policy makers
Association of Alzheimer’s related genotypes with cognitive decline in multiple domains: results from the Three-City Dijon study
In a large prospective population-based study of dementia-free individuals, only a few cognitive domains were associated with established LOAD risk alleles, and the most consistent associations were for global cognition and verbal fluency.