• Publications
  • Influence
Self-injection of apomorphine in the rat: positive reinforcement by a dopamine receptor stimulant.
Abstract Rats with jugular cannulas self-administer the dopamine receptor stimulant apomorphine at doses from 0.125 to 1 mg/kg/injection. Pretreatment with the dopamine receptor blocker pimozide (0.5Expand
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Animal pharmacology of Wy-16,225, a new analgesic agent.
The analgesic potency of Wy-16,225 in rodents and primates is greater than morphine while antagonist potency is slightly less than that of nalorphine. The compound demonstrates properties unlikeExpand
  • 47
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Enhanced analgesic activity of D-Ala2 enkephalinamides following D-isomer substitutions at position five.
Abstract The analgesic potency of D-Ala 2 , Met 5 - and D-Ala 2 , Leu 5 -enkephalinamide was increased following substitution of the D-isomers at position five. The substituted analogs were 2.5 timesExpand
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Specificity of social-anthropological studies of ritual.
  • M. Gluckman
  • Sociology, Medicine
  • Mental health and society
  • 1975
Many fruitless controversies about 'ritual' are based on the multivocality of the word. By recent work by Tinbergen in ethology confines the term to rigid, highly formalistic, exaggerated behavior byExpand
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Cerebral synaptic inhibition by serotonin and iproniazid.
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The actions of barbiturates on the contractions of voluntary muscle.
Four types of effects on voluntary muscle function have been shown to be evoked by relatively low concentrations of the barbiturates, the incidence and intensity of the effect varying with theExpand
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The topical anti‐inflammatory effects of a topical preparation of meclofenamic acid on carrageenan‐induced footpad swelling in mice
A topical preparation of meclofenamic acid (Meclomen) was tested for anti‐inflammatory activity in a murine model of carrageenan footpad oedema. The preparation significantly inhibited swelling whenExpand
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General pharmacologic actions of the antihypertensive agent 2,6-dichlorobenzylidene aminoguanidine acetate (WY-8678).
Wy-8678 has been shown to lower blood pressure and heart rate in unanesthetized hypertensive animals. The present study describes the general cardiovascular actions of the compound. IntravenousExpand
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The effects of thiopental and pentobarbital on voluntary muscle.
Thiopental and pentobarbital cause potentiation of the maximal twitch of the dog and cat tibial muscle, thiopental being the more active drug. This effect is possibly mediated through a slowing ofExpand
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Selective inhibition of the cyclooxygenase pathway of the arachidonic acid cascade by the nonsteroidal antiinflammatory drug isoxicam
The effects of the nonsteroidal antiinflammatory drug isoxicam on prostaglandin formation by HSDM1C1 mouse fibrosarcoma cells grown in culture and 5‐HETE(5(S)‐5‐hydroxy‐6‐trans, 8,11,14‐cisExpand
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